Retrospective analysis of patients with locally advanced esophageal cancer with involvement of the tracheobronchial tree who have received neoadjuvant chemotherapy

il0 个研究点目标入组 100 人开始时间: 待定最近更新: 2021年11月24日

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•We will include all patients who have esophageal cancer and evidence of airway involvement, who are planned for induction chemotherapy, followed by reassessment.
•Airway involvement is defined as at least one of the following criteria:
•1. Bronchoscopic appearance of external compression or bulge into the tracheal or bronchial lumen, in a patient in whom upfront chemoradiotherapy or radiotherapy was not offered, and who was planned for induction chemotherapy
•2. Bronchoscopic appearance of restricted mobility or immobility of the mucosa of the trachea or bronchi, in a patient in whom upfront chemoradiotherapy or radiotherapy was not offered, and who was planned for induction chemotherapy
•3. Bronchoscopic appearance of endotracheal or endobronchial tumor.
•4. Clinical diagnosis of stridor, when other causes of stridor have been ruled out and the cause of stridor is clinically due to airway obstruction.
•We will include patients who have started chemotherapy from Nov 2010 onwards to 15 Jan 2015.

•Patients who are planned for palliative intent therapy or best supportive care.

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