Effect of Blood Flow Restriction (BFR) on Rehabilitation Protocols Following Anterior Cruciate Ligament Reconstruction (ACLR) With Quadricep Autograft
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Quad muscle Strength
研究概览
简要总结
This project is intended to acquire objective measurements of implementing BFR rehabilitation in ACL reconstructions to show any changes upon completion of the BFR protocol. The results in this study will hopefully represent valuable data in the support of using autografts for ACL reconstructions in high level athletes wanting a full recovery and return to high level of sport.
It has been speculated that use of autografts in ACL reconstructions leads to more quad weakness and muscle atrophy due to tendon harvesting. (Slone et al., 2015) More recently, BFR has shown promise in expediting the recovery and rehabilitation process post-surgically. By implementing BFR following ACL reconstructions with autografts, we hope to mitigate the major deterrent for autograft use and giving patients a more cost-effective approach to surgery. (Hughes et al., 2019)
详细描述
Specific Aim 1 will identify the overall preservation of muscle and changes in body composition after injury and throughout surgical rehabilitation in athletes undergoing ACL reconstruction. It is hypothesized that implementing BFR rehabilitation protocols following ACL reconstruction with autografts will expedite recovery and return to sport and rescue of muscle tissue at the donor site.
Specific Aim 2 will monitor muscle strength and activation following ACL reconstruction with performance of standardized assessments at intervals. It is hypothesized that BFR implementation will show greater return to strength and enhanced muscle activation during testing.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 14 Years 至 40 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient undergoing anterior cruciate ligament construction utilizing a quadriceps autograft
- •Age 14 - 40 years old
排除标准
- •Comorbid conditions (i.e.: hypertension, diabetes, obesity, etc.)
- •Patient taking blood thinners or at risk of embolism
- •Revision anterior cruciate ligament construction
- •Allograft based reconstruction
- •Non-quadriceps graft
结局指标
主要结局
Quad muscle Strength
时间窗: At 6 week post surgical timepoints
Compare the muscle strength gain or loss between BFR group and control group
Return to sport
时间窗: 6 week intervals
Compare the time it takes participants to return to sport in BFR group to control group
次要结局
未报告次要终点
研究者
Matthew Vopat
Assistant Professor, Orthopedic Surgery
University of Kansas Medical Center