Detection in Peripheral Blood of Circulating Tumor Cells in Patient With Head and Neck Squamous Cell Carcinoma

Institut de Cancérologie de Lorraine1 site in 1 country40 target enrollmentDecember 8, 2010

ConditionsHead and Neck Cancer

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Head and Neck Cancer
Sponsor: Institut de Cancérologie de Lorraine
Enrollment: 40
Locations: 1
Primary Endpoint: Circulating tumor cells in peripheral blood during head and neck surgery
Status: Completed
Last Updated: 7 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The dissemination of individual tumor cells is a common phenomenon in solid cancers. Detection of tumor cells in peripheral blood circulating tumor cells (CTC) in nonmetastatic situation is of high prognostic significance.

The objective of our study was to detect circulating tumor cells in two different method in patient with head and neck squamous cell carcinoma .

Registry

clinicaltrials.gov

Start Date

December 8, 2010

End Date

April 2018

Last Updated

7 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Institut de Cancérologie de Lorraine

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Age ≥ 18 years
•Patient with head and neck squamous cell cancer stage III or IV histologically proven
•Patient naive to any prior therapy
•Patient with operate cancer and resectable tumor
•Hemoglobin ≥ 10g / dL
•Performance status ≤ 2
•Ability to provide written informed consent
•Patient's legal capacity to consent to study participation

Exclusion Criteria

•Other previous histology tumors
•Medical conditions or acute or chronic severe psychiatric disorders
•Deprived of liberty or under supervision

Outcomes

Primary Outcomes

Circulating tumor cells in peripheral blood during head and neck surgery

Time Frame: 7 days

The number of circulating tumor cells detected per milliliter of peripheral blood will be evaluated on the day before, the day of surgery and 7 days after the surgery.