Nd:YAG vs Alexandrite Laser Treatment in Hidradenitis Suppurativa
- Conditions
- Hidradenitis Suppurativa (HS)
- Registration Number
- NCT06960447
- Lead Sponsor
- Geisinger Clinic
- Brief Summary
The purpose of this study is to evaluate whether Alexandrite laser treatment is non-inferior to Nd:YAG (neodymium-doped yttrium aluminum garnet) laser treatment of hidradenitis suppurativa (HS).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 21
- Geisinger male or female patients with a diagnosis of hidradenitis suppurativa (all stages of disease)
- 12-75 years of age
- Not on concurrent systemic therapy (e.g., antibiotics, biologic therapies)
- Must have not used systemic therapies within 2 weeks of enrollment in study
- Able and willing to provide consent
- Patients who cannot tolerate laser therapy
- Patients who cannot wear protective eyewear
- Patients who are pregnant
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method HiSCR50 6 months Percentage of patients achieving a 50% reduction in their hidradenitis suppurativa clinical response (HiSCR) score.
HiSQOL 6 months The Hidradenitis Suppurativa Quality Of Life (HiSQOL) scale, a validated HS quality of life index and is comprised of a 17-item HS-specific HRQOL instrument with a 7-day recall period. Score ranges from 0 to 68, with higher scores indicating more severe impact
- Secondary Outcome Measures
Name Time Method Pain VAS score 6 months Visual analogue score for pain ranging from 0-10 with higher scores indicating worse pain.
Pruritus numeric rating scale 6 months As measured by a numeric rating scale from 0-10 with higher scores indicating worse itching.
Days free of disease in last 30 days 6 months The number of days a patient has not had a flare of HS in the past 30 days.
AN Count 6 months Number of abscesses and nodules on exam