Exploratory research on effectiveness and safety of Rituximab treatment for steroid intractable pemphygus, bullous pemphigoid and epidermolysis bullosa acquisita.
Phase 2
- Conditions
- pemphigus, bullous pemphigoid, epidermolysis bullosa acquisita
- Registration Number
- JPRN-UMIN000004428
- Lead Sponsor
- Research group of rare intractable dermatologial disorder
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
Health condition 1) Pregnancy 2) Allergy for biologics 3) Severe organ disorder 4) History of other diseases which need systemic steroid treatment 5) Infections 6) Malignancy Treatment history 1) Use of biologics 2) Severe adverse events by immunosuppressant (CTCAE over grade 3)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1) A rate of severe adverse events, beyond CTCAE grade 3. 2) A rate of remission
- Secondary Outcome Measures
Name Time Method