An efficacy and safety study comparing the fixed combination of two antihypertensive agents, indapamide and amlodipine in a single-pill, to the same drugs given separately, in patients with mild to moderate uncontrolled essential hypertensio

Not Applicable

Completed

• Conditions: Essential hypertension; Circulatory System; Essential (primary) hypertension

• Registration Number: ISRCTN63697536
• Lead Sponsor: Institut de Recherches Internationales Servier (France)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-04-28
• Study Completion: 2015-01-31
• Last Update Posted: 21 May 2018

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

­1. Men or women of any ethnic origin, 18 years or older
­2. Mild to moderate essential combined systolic and diastolic hypertension or isolated systolic hypertension

Exclusion Criteria

1. Pregnancy, breastfeeding or possibility of becoming pregnant during the study
2. Orthostatic hypotension
3. Hypertension known to be resistant to diuretics and calcium channel inhibitors (given separately or in combination)
4. Secondary hypertension
5. Complicated hypertension
6. Diabetes mellitus type I and type II under treatment
7. Any history or known severe disease likely to interfere with the conduct of the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified