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Study Comparing Weekly Taxol and Carboplatin vs Standard Taxol and Carboplatin Regimen for Stage IIIB or IV Non-Small-Cell Lung Cancer

Phase 3
Completed
Conditions
Carcinoma, Non-Small-Cell Lung
Registration Number
NCT00035152
Lead Sponsor
Bristol-Myers Squibb
Brief Summary

Taxol and carboplatin are commonly used drugs for the treatment of stage IIIB or IV non small cell lung carcinoma.

This study compares treatment with Taxol/carboplatin given every 3 weeks to a schedule where it is given weekly.

The purpose of the study is to determine the most effective and safe schedule for giving these drugs in non small cell lung carcinoma.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
444
Inclusion Criteria

Not provided

Exclusion Criteria
  • Past or current history of neoplasm other than the entry diagnosis. Exceptions are curatively treated basal cell or squamous cell skin cancer, carcinoma in situ of the cervix or other cancers treated by surgery or radiation with a disease free survival longer than 5 years.
  • Patients who have undergone surgery less than 3 weeks prior to enrollment.
  • History of serious cardiac disease not adequately controlled.
  • Patients with serious active infections or other serious underlying medical condition.
  • Uncontrolled diabetes mellitis.

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (56)

Genesis Cancer Center

🇺🇸

Hot Springs, Arkansas, United States

Little Rock Hematology/Oncology Associates

🇺🇸

Little Rock, Arkansas, United States

Highlands Oncology Group

🇺🇸

Springdale, Arkansas, United States

Medical Oncology Care Associates

🇺🇸

Orange, California, United States

Naval Medical Center

🇺🇸

San Diego, California, United States

Danbury Hospital/Praxair Cancer Center

🇺🇸

Danbury, Connecticut, United States

Walter Reed Army Hospital

🇺🇸

Washington, District of Columbia, United States

Washington VA Medical Center

🇺🇸

Washington, District of Columbia, United States

Good Samaritan Medical Center

🇺🇸

West Palm Beach, Florida, United States

Wellstar Cobb Hospital

🇺🇸

Austell, Georgia, United States

Scroll for more (46 remaining)
Genesis Cancer Center
🇺🇸Hot Springs, Arkansas, United States

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