Role of USG guided transversus abdominis plane block with different adjuvants in enhancing postoperative analgesia in total abdominal hysterectomy
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 入组人数
- 69
- 试验地点
- 1
- 主要终点
- To assess the duration of postoperative analgesia and requirement of first
研究概览
简要总结
Abdominal hysterectomy is open surgical procedure associated with considerable post operative pain. The use of transverse lower abdominal incisions in hysterectomies and myomectomies often cause severe pain during first 48 hours postoperatively which can adversely impact healing, patient outcomes and prolong the length of hospital stay .More recently multimodal analgesia like tap blocks has been providing better post operative pain relief. Ropivacaine is an amide local anesthetic with better sensory and motor blocking profiles and with low toxicity potential. Dexmedetomidine is an selective alpha 2 adrenergic agonist with sedative and analgesic properties. Dexamethasone as an adjuvant causes early onset and prolongs the duration of analgesia. Thus in our current study we aim to assess the efficacy of 0.25 ropivacaine and compare it with dexamethasone and dexmedetomidine in USG guided TAP block in providing post operative analgesia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 45.00 Year(s) 至 80.00 Year(s)(—)
- 性别
- Female
入选标准
- •patients of ASA-1 and 2 undergoing total abdominal hysterectomy under spinal anesthesia.
排除标准
- •Patient refusal to participate in the study
- •Infection at the block site.
- •Neurological deficit in lower limbs.
- •Altered coagulation status
- •Patients with heart blocks
- •Patients taking analgesics for other reasons.
结局指标
主要结局
To assess the duration of postoperative analgesia and requirement of first
时间窗: till 24 hours post surgery
rescue analgesic.
时间窗: till 24 hours post surgery
次要结局
- To assess the cumulative consumption of additional analgesia in 12 and(24 hours in both the groups.)
