Optimization of intracoronary functional coronary lesion severity evaluation by simultaneous intracoronary pressure and flow velocity measurements during baseline conditions, and contrast medium- or regadenoson- induced hyperemia. - IMPROVE

Academisch Medisch Centrum0 个研究点目标入组 200 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

暂无简介。

•1. Stable angina (CCS class I to 3, or Braunwald class I)
•2. Scheduled for PCI or intracoronary evaluation of functional lesion severity (diagnostic catheterization) of at least one coronary lesion in a native coronary vessel of 40 * 80% diameter stenosis on visual estim

•1. Younger than 18 or older than 80 years of age
•2. Multiple coronary lesions in the same coronary artery
•3. Recent myocardial infarction or revascularization (less than 6 weeks prior to procedure)
•4. Previous revascularization of the vessel of interest
•5. Severe left ventricular dysfunction (LV ejection fraction less than 30%)
•6. Severe renal insufficiency (eGRF according to sMDRD less than 30 mL/min/m2)
•7. 50% or more diameter stenosis in left main coronary artery
•8. Severe valvular abnormalities
•9. Women of childbearing age without a negative pregnancy test or active birthcontrol

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