Acute Effects of Whole-Body Vibration on Pain, Neuromuscular Performance and Gait Quality in Patients with Knee Osteoarthritis. a Randomized Controlled Trial.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Changes in pain of the osteo-arthrotic knee
研究概览
简要总结
Knee osteoarthritis is a chronic joint disease with an impact on quality of life and an increasing incidence what leads to huge costs and burden on the economy.
The present study investigates immediate effects of whole-body vibration on pain, neuromuscular performance, and gait quality in patients with knee osteoarthritis. Eligible patients (n=20) with knee osteoarthritis grade 2 or 3 on Kallgren Lawrence will complete a 5 minute WBV training and a control condition in a randomized order (cross over design). Pain, maximum strength of the leg flexors and extensors, the chair rise test and gait parameters will be measured directly before and after the intervention/control.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
Outcome assessor were unaware of participants status and were not allowed to ask correpondingly
入排标准
- 年龄范围
- 40 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •x-ray confirmed knee osteoarthritis (Kallgren-Lawrence 2-3)
- •knee pain (NRS 0-10 >2) for 3 months and at least 50% of the last 30 days
排除标准
- •contraindications for WBV (acute injuries of the musculoskeletal system, new joint endoprosthesis, pregnancy, acute thrombosis, Epilepsia, cholecystolithiasis, nephrolithiasis, heart pace maker),
- •other pathologies affecting gait or neuromuscular performance (rheumatic
- •opioid medications, cortisol medications and intraarticular injections in the knee during the ist 3 months.
结局指标
主要结局
Changes in pain of the osteo-arthrotic knee
时间窗: Changes in pain of the osteoarthrotic knee during the treadmill test as determined on a visual analogue scale (VAS 0-10) before and after 5 min of intervention
Changes in pain of the osteo-arthrotic knee during the treadmill test as determined on a visual analogue scale (VAS 0-10).
次要结局
- Changes in isometric maximum leg flexion strength of the osteoarthritis knee(Changes in isometric maximum leg flexion strength of the osteoarthritis knee before and after 5 min of Intervention.)
- Changes in isometric maximum leg extension strength of the osteoarthritis knee(Changes in isometric maximum leg extension strength of the osteoarthritis knee before and after 5 min of Intervention)
- Changes of number of repetitions in the 30 s sit to stand (chair rise) test(Changes in number of repetitions in the 30 s sit-to-stand test before and after 5 min of intervention)
- Changes of ipsilateral stride length(Changes of ipsilateral stride length (cm) at treadmill as determined by the 4D motion high-performance lab ( (Firma Diers Formetric, Germany) before and after 5 min of Intervention)
- Changes of ipsilateral stride time(Changes of ipsilateral stride length (cm) at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany) before and after 5 min of intervention.)
- Changes of stride width(Changes of stride width (cm) at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany) before and after 5 min of intervention.)
- Changes of ipsilateral stance time(Changes of ipsilateral stance time (%) at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany) before and after 5 min of intervention)
- Changes of ipsilateral single support time(Changes of ipsilateral single support time (%) at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany) before and after 5 min of intervention)
- Changes of double support time(Changes of double support time (%) at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany) before and after 5 min of intervention)
- Changes of trunk inclination(Changes of trunk inclination (mm) at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany) before and after 5 min of intervention)
- Changes of ipsilateral und kontralateral knee angle in frontal plane(Changes of ipsilateral und kontralateral knee angle (°) in frontal plane at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany) before and after 5 min of intervention)
- Changes of ipsilateral und kontralateral knee angle in sagital plane(Changes of ipsilateral und kontralateral knee angle in sagital plane (°) at treadmill as determined by the 4D motion high-performance lab (Firma Diers Formetric, Germany) before and after 5 min of intervention)
研究者
Wolfgang Kemmler, PhD
Head of Research
Friedrich-Alexander-Universität Erlangen-Nürnberg