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Clinical Trials/NCT02284152
NCT02284152
Completed
N/A

Responsive Feeding Study

Drexel University3 sites in 1 country32 target enrollmentJanuary 2010
ConditionsBottle Feeding

Overview

Phase
N/A
Intervention
Not specified
Conditions
Bottle Feeding
Sponsor
Drexel University
Enrollment
32
Locations
3
Primary Endpoint
Infant Intake
Status
Completed
Last Updated
11 years ago

Overview

Brief Summary

In the present study, we tested a novel approach to understanding infant bottle-feeding interactions: experimentally manipulating bottle-feeding conditions to better understand maternal and infant influences on overfeeding, as well as individual differences in risk for overfeeding. Specifically, we observed mother-infant dyads during a typical, "mother-led" feeding, during which mothers were given no instruction regarding how or how much to feed their infants (hereafter referred to as a "typical feeding" [TF]), as well as during an "infant-led" (IL) feeding, wherein we minimized the mothers' influence on the feeding and ensured the feed was in response to the infants' hunger and fullness cues. Using this within-subject, objective, and experimental approach, the present study aimed to: 1) directly measure the extent to which overfeeding occurs during bottle-feeding and 2) describe the characteristics of infants and mothers that overfeed during bottle-feeding.

Detailed Description

Each mother-infant dyad came to our laboratory on two different days, separated by an average of 2.1 ± 0.4 days. The two testing sessions occurred at the same time of day to control for infants' circadian rhythmicity. Mothers were instructed to bring two of their infants' typical bottles filled with their infants' typical formula to each testing session. Mothers were videotaped while feeding their infants on both days. The first day of testing was always the Typical Feeding (TF) condition because the only instruction given to the mother was: "Please feed your infant as you normally would at home." The second day of testing was always the Infant-Led (IL) condition, wherein we used a protocol developed and established in our laboratory to control for a number of factors to allow for evaluation of infants' hedonic and behavioral responses independent of the parent and experimenter. The feeding protocol during the IL condition entailed the following steps, which were facilitated by the experimenter: (1) feeding sessions began when the experimenter observed the infant displaying signs of hunger (e.g., mouthing, rooting, fussing) and the mother verified that the infant was hungry; (2) the mother was instructed not to talk to her infant and to remain as neutral as possible; (3) the mother was also instructed to feed her infant at his/her customary pace; (4) the experimenter ended the feeding when the infant displayed signs of fullness (e.g., turning head and/or body away from the bottle, biting or chewing on the nipple, spiting the nipple out) on at least three consecutive occasions. If the infant finished the bottle before signaling fullness, the experimenter gave the mother the other bottle to ensure that infant intake was not limited by formula availability. During both study days, consumption during the feeding session was assessed by weighing the bottles before and after each feeding using a top loading balance (model PM 15; Mettler, Greifensee, Switzerland).

Registry
clinicaltrials.gov
Start Date
January 2010
End Date
March 2012
Last Updated
11 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Alison Ventura

Assistant Professor

Drexel University

Eligibility Criteria

Inclusion Criteria

  • Formula-feeding
  • Prior to the introduction of solid foods
  • Infants 0 to 6 months of age
  • Mothers 18 to 40 years of age

Exclusion Criteria

  • Exclusively breast-feeding
  • Medical conditions that interfered with feeding

Outcomes

Primary Outcomes

Infant Intake

Time Frame: 3-hour period

Infant intake was assessed by weighing the bottle before and after the feeding

Study Sites (3)

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