Beta Blocker Use in Cardiac Surgery and Association With Postoperative Course

Completed

• Conditions: Cardiac Surgery With Cardiopulmonary Bypass
• Interventions: Other: collection of the allocated treatment; Other: collection of medical complications

• Registration Number: NCT04769752
• Lead Sponsor: Centre Hospitalier Universitaire Dijon

Brief Summary

The objective of this study is to describe in a cohort of cardiac surgery patients the use of beta-blockers before surgery and their maintenance or withdraw according to international recommendations in order to compare patients who receive a beta-blocker with maintenance during the surgical period (international recommendation) to those for whom prescription and maintenance are not respected. Patients are treated according to standard practice and this protocol does not change patient management. No additional information or data is required by the study other than the data usually collected in the patient record (drug treatment, medical history, operating data, postoperative data, complications, length of stay).

The objectives of this research are :

* To evaluate the proportion of patients receiving beta-blocker treatment prior to cardiac surgery.

* To evaluate the proportion of patients receiving beta-blocker treatment before cardiac surgery and complying with international recommendations for its maintenance/stop in perioperative cardiac surgery.

* To evaluate the incidence of complications and length of hospital stay in patients receiving beta-blockers based on compliance or non-compliance with recommendations.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-06
• Study First Submitted: 2021-02-23
• Study First Submitted QC: 2021-02-23
• Study First Posted: 2021-02-24
• Status Verified: 2023-02
• Primary Completion: 2023-12-22
• Study Completion: 2023-12-22
• Last Update Submitted: 2024-02-15
• Last Update Posted: 2024-02-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1789

Inclusion Criteria

• Major patient ≥ 18 years
• Patient operated cardiac surgery with cardiopulmonary bypass
• Patients who have given oral consent to participate after full information

Exclusion Criteria

• Off pump cardiac surgery

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
No beta-blocker	collection of the allocated treatment	Patient do no treat with beta-blocker before the surgery
Beta blocker	collection of the allocated treatment	Patient treat with beta-blocker in accordance to international guidelines
No beta-blocker	collection of medical complications	Patient do no treat with beta-blocker before the surgery
Beta blocker	collection of medical complications	Patient treat with beta-blocker in accordance to international guidelines

Primary Outcome Measures

Name	Time	Method
Number of patients treated with beta-blocker in accordance with international guidelines	7 days	Number of patients treated with beta-blocker in accordance with international guidelines

Trial Locations

Locations (1)

Chu Dijon Bourogne; 🇫🇷 Dijon, France