Interest of the Chair Lift Test in the Prognostic Evaluation of Pulmonary Embolism: a Single-center Open Prospective Study

University Hospital, Rouen1 个研究点分布在 1 个国家目标入组 180 人2024年2月9日

适应症Non-severe Pulmonary Embolism

干预措施chair lift test

概览

阶段: 不适用
干预措施: chair lift test
疾病 / 适应症: Non-severe Pulmonary Embolism
发起方: University Hospital, Rouen
入组人数: 180
试验地点: 1
主要终点: sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of the one-minute chair rise test in comparison with the gold standard refined by the use of cardiac biomarkers and right ventricular dysfunction
状态: 招募中
最后更新: 2个月前

概览研究者入排标准研究组 & 干预措施结局指标研究点相似试验

概览

简要总结

The objective of the study is to evaluate the prognostic performance of the chair lift test in the initial assessment of the severity of non-severe pulmonary embolism in hospitalized patients, in comparison with the current pulmonary embolism risk stratification score using the sPESI score refined by the use of cardiac biomarkers and right ventricular dysfunction

注册库

clinicaltrials.gov

开始日期

2024年2月9日

结束日期

2027年2月1日

最后更新

2个月前

研究类型

Interventional

研究设计

Single Group

性别

All

研究者

发起方

University Hospital, Rouen

责任方

Sponsor

入排标准

入选标准

•Diagnosis of pulmonary embolism according to clinical algorithm, confirmed by thoracic angioscan or ventilation perfusion (V/P) scan,
•Non-serious pulmonary embolism, not requiring intensive care (thrombectomy or fibrinolysis not considered).
•sPESI score ≥ 1 \[or = 0 with elevated troponin or presence of markers of VD dysfunction, or = 0 with need for hospitalization due to comorbidities unrelated to PE (social isolation, comprehension disorders, intercurrent infection, chronic renal failure, advanced cancer...)
•Patients with no contraindications to chair lift testing (no O2 at the time of testing).
•Effective anticoagulation for at least 1 hour.

排除标准

•sPESI score = 0 with outpatient referral.
•Diagnostic confirmation of Pulmonia Embolism by thoracic angioscan or scintigraphy more than 24h after suspicion of diagnosis.
•Hospitalization \> 24h after introduction of anticoagulation, with subsequent confirmation by scintigraphy.
•Any sign of serious Pulmonia Embolism, requiring hospitalization in an intensive care unit.
•Asymptomatic Pulmonia Embolism discovered by chance

研究组 & 干预措施

chair lift test

干预措施: chair lift test

结局指标

主要结局

sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of the one-minute chair rise test in comparison with the gold standard refined by the use of cardiac biomarkers and right ventricular dysfunction

时间窗: 1 day