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Clinical Trials/NL-OMON35451
NL-OMON35451
Completed
N/A

Optimization of Cardiac Resynchronization Therapy at rest and during exercise conditions. - OPTI-CARE

niversitair Medisch Centrum Utrecht0 sites51 target enrollmentTBD

Overview

Phase
N/A
Intervention
Not specified
Conditions
Not specified
Sponsor
niversitair Medisch Centrum Utrecht
Enrollment
51
Status
Completed
Last Updated
last year

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
last year
Study Type
Observational invasive

Investigators

Sponsor
niversitair Medisch Centrum Utrecht

Eligibility Criteria

Inclusion Criteria

  • Indication for Cardiac Resynchronization Therapy according to the current international guidelines. (See research protocol: chapter 5\.2\)

Exclusion Criteria

  • Criteria for the complete study: (see also research protocol chapter 5\.3\)
  • \-Contraindications for implantation of a CRT device;
  • \-Age \<18 years or incapacitated adult;
  • \-Participation in another clinical study that prohibits any procedures other than standard;
  • \-Pregnancy;
  • \-Severe aortic stenosis with a valve area \<1,0 cm2 or aortic valve replacement in history.;Specific criteria for the infusion of dobutamine (see research protocol chapter 5\.3 and 6\.2\.1\):
  • \-Significant abnormalities on coronary angiogram or myocardial perfusion scan (part of standard procedure before CRT implantation) that are not treated by coronary artery bypass graft or percutaneous coronary intervention;
  • \-Atrial fibrillation with a fast ventricular response (heart rate \>100 bpm);
  • \-Baseline heart rate \<10 beats per minute below target heart rate;
  • \-Sinus bradycardia \<40 beats per minute at baseline;

Outcomes

Primary Outcomes

Not specified

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