NCT07335029进行中（未招募）不适用
Investigation of Hemodynamics and Radiomics Based on High Resolution Magnetic Resonance Imaging for Predicting the Outcomes of Intracranial Dissecting Aneurysm
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 208
- 试验地点
- 1
- 主要终点
- Progression of intracranial dissecting aneurysms
研究概览
简要总结
This study aims to conduct a comprehensive analysis by integrating clinical factors, aneurysm morphological characteristics, and factors reflecting pathophysiological processes (such as hemodynamic and radiomics features), in order to explore the hemodynamic mechanisms associated with the progression of intracranial dissecting aneurysms. Furthermore, artificial intelligence algorithms will be employed to develop and validate an intelligent risk prediction model for the progression and outcomes of intracranial dissecting aneurysms.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Intracranial dissecting aneurysm clearly diagnosed by DSA and high-resolution MRI imaging (according to the imaging diagnostic criteria proposed in the Chinese Expert Consensus on Imaging Diagnosis of Intracranial Arterial Dissection)
- •patients managed with conservative treatment and follow-up
- •patients who agree and sign a written informed consent form
排除标准
- •Arteritis, fibromuscular dysplasia, iatrogenic or traumatic pseudoaneurysms
- •Contraindications to MRI examination (such as claustrophobia or metallic implants), or contraindications to cerebral angiography (such as iodine contrast allergy)
- •Dissecting aneurysms extending from the extracranial segment to the intracranial segment, or cases with concomitant intracranial atherosclerotic plaques in the affected vessels
- •Patients who refuse MRI examination
- •Patients with severe comorbid diseases and an expected survival time of less than 2 years due to these conditions
- •Patients without follow-up HR-MRI imaging for any reason
结局指标
主要结局
Progression of intracranial dissecting aneurysms
时间窗: From enrollment to 12 months of follow-up
次要结局
未报告次要终点
研究者
Li wenqiang
Doctor
Beijing Neurosurgical Institute
研究点 (1)
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