Efficacy of celecoxib in the treatment of bipolar disorder
Phase 2
- Conditions
- Bipolar Disorder.Mania episode
- Registration Number
- IRCT201307171556N53
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
meeting the DSM-IV criteria for Bipolar Disorder; age between 18 and 65 years; a score of at least 20 points on the Young Mania Rating Scale;
Exclusion criteria: hyper- or hypothyroidism; substance dependence(except for Nicotine); IQ lower than 70; history of allergy to Celecoxib; lactating and pregnant women; gastro-intestinal ulcer or hemorrhage; cerebrovascular hemorrhage; severe hepatic disease
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of mania. Timepoint: Baseline and weerks 1, 2, 4, 6. Method of measurement: by Young Mania Rating Scale.
- Secondary Outcome Measures
Name Time Method Severity of extrapyramidal side effects. Timepoint: Baseline and weerks 1, 2, 4, 6. Method of measurement: By Extrapyramidal Symptom Rating Scale(ESRS).