NCT04974983已完成不适用
Impact of Bevacizumab on Symptom Burden and Neurological Deficits in Patients With Recurrent GBM: A Retrospective Patient Chart Review
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 203
- 试验地点
- 1
- 主要终点
- Functional outcome
研究概览
简要总结
This retrospective non - interventional patient chart review will be utilizing real world clinical data from patients treated for rGBM at the University Regensburg Medical center either with or without bevacizumab. Only patients will be analyzed who were potentially eligible for bevacizumab treatment. The study is designed to investigate the potential effects of bevacizumab treatment on the functional status, symptom burden, neurological deficits, time to tumor progression and overall survival between cohorts potentially eligible for bevacizumab.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of recurrent glioblastoma
排除标准
- •Severe neurocognitive deficits
结局指标
主要结局
Functional outcome
时间窗: 15 months
Neurological deficits impacting functional independency
次要结局
未报告次要终点
研究者
Martin Proescholdt
Professor of Neurosurgery
University Hospital Regensburg
研究点 (1)
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