Fluorescent angiography using indocyanine green during esophagectomy with continuity restoration to prevent anastomotic complications
Recruiting
- Conditions
- Esophageal cancer
- Registration Number
- NL-OMON24815
- Lead Sponsor
- one
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 70
Inclusion Criteria
Age of 18 years and older;
-Undergoing esophagectomy with gastric conduit reconstruction;
-Undergoing esophagectomy with continuity restoration, graft other than gastric conduit;
-Intraoperative FA to assess perfusion of graft and anastomosis;
-No objection for use of data.
Exclusion Criteria
-Allergy to ICG, iodide or sodium iodide;
-Hyperthyroidism or benign thyroid tumor;
-Thyroid examination using radioactive iodide <1 week;
-Breast-feeding;
-Objection for use of data.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcomes are various quantitative parameters of FA, and to relate those parameters to surgical morbidity. Quantitative parameters include time to fluorescence in target or surrounding tissue.
- Secondary Outcome Measures
Name Time Method Secondary outcomes include surgical morbidity, other FA details, and hemodynamic parameters. Surgical outcomes include anastomotic leakage, graft necrosis and anastomotic strictures. FA details include change in management and additional surgical time.