An Integrative Multi-Omic Characterization of Head and Neck Carcinogenesis, Progression and Recurrence
Recruiting
- Conditions
- Head and Neck Carcinoma
- Interventions
- Other: Non-Interventional Study
- Registration Number
- NCT06420219
- Lead Sponsor
- University of Southern California
- Brief Summary
This study evaluates the cell and biomarkers associated with the aggressive behavior of cancer.
- Detailed Description
PRIMARY OBJECTIVE:
I. High-resolution single-cell profiling of Cancer-associated fibroblasts (CAFs) in Human papillomavirus (HPV)+ Oropharyngeal Squamous Cell Carcinoma (OPSCC) and metastatic lymph nodes.
OUTLINE: This is an observational study.
Patients undergo photography, blood sample collection, tissue collection and have their medical records reviewed on study.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
- Diagnosis/disease status: New diagnosis of head and neck cancer
- Allowable type and amount of prior therapy: No prior treatment
- Age ≥ 18 years.
- Ability to understand and the willingness to sign a written informed consent.
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Exclusion Criteria
- Patients who have had treatment of head and neck cancer
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Observational Non-Interventional Study Patients undergo photography, blood sample collection, tissue collection and have their medical records reviewed on study.
- Primary Outcome Measures
Name Time Method Overall survival Up to 5 years Disease free survival Up to 5 years
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
USC / Norris Comprehensive Cancer Center
🇺🇸Los Angeles, California, United States