NCT03020706Unknown不适用
Effect of Magnesium Sulphate on Neostigmine-induced Reversal of Neuromuscular Block by Rocuronium
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 入组人数
- 166
- 试验地点
- 1
- 主要终点
- reversal time
研究概览
简要总结
The purpose of this study is to evaluate the effect of magnesium sulphate on neostigmine-induced reversal of neuromuscular block by rocuronium
详细描述
Comparison of reversa time by neostigmine in magnesium group and control group
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 20 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •ASA status 1 or 2
- •patients undergoing surgery for more than 60 min under general anesthesia
排除标准
- •electrolyte abnormalities
- •medication on aminoglycoside, antiepileptic drug, magnesium
- •underweight or obesity (BMI <18.5 or >30)
- •renal insufficiency (Cr>1.4 mg/dl)
- •neuromuscular disease (ex: Myathenia gravis)
研究组 & 干预措施
Magnesium
Experimental
magnesium sulfate, injectable intravenous administration (50mg/kg diluted in 100ml normal saline) during general anesthesia
干预措施: Magnesium Sulfate, Injectable (Drug)
结局指标
主要结局
reversal time
时间窗: through study completion, an average of 90 minutes
reversal time: from neostigmine injection to TOF ratio 0.9
次要结局
未报告次要终点
研究者
Park Hee-Yeon
Associate professor
Gachon University Gil Medical Center
研究点 (1)
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