Dietary Insights and Nutrition Experiences in Adults on GLP-1 Therapy - A Study on Diet Quality Changes in Adults on GLP-1 Therapy
Trial Snapshot
- Phase
- Not Applicable
- Status
- Active, not recruiting
- Sponsor
- University of South Carolina
- Enrollment
- 50
- Locations
- 2
- Primary Endpoint
- Change in Healthy Eating Index
Study Overview
Brief Summary
The DINE-GLP1 study aims to understand how people on GLP-1 therapy change their eating habits and what kind of dietary support they need. As more people use GLP-1 medications, there's not much guidance on what they should eat, mostly just focusing on managing symptoms and cutting calories. Since these medications reduce food intake, it's important to ensure the diet is nutritious even with fewer calories to help with long-term weight control and health. Most research has looked at how the body responds to the medication and whether patients take it as prescribed, but not much is known about what patients actually experience, what they think they need, or how they could use additional support. Understanding patients' views can help create better lasting solutions. Note that this study does not provide free GLP-1 medication.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Cross Sectional
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Adults aged 18 and older
- •Recently has been prescribed GLP-1 therapy for the treatment of obesity or T2DM but have not yet initiated the medication
- •Has regular access to a smartphone and internet to complete short surveys and food recalls online
- •Willing to sign informed consent.
Exclusion Criteria
- •Already began the GLP-1 medication
- •Have medical concerns making participation unsafe
Arms & Interventions
GLP-1 Therapy
Individuals prescribed with GLP-1 Therapy for obesity or T2DM management.
Intervention: GLP-1 Therapy (Drug)
Outcomes
Primary Outcomes
Change in Healthy Eating Index
Time Frame: Baseline and 12-weeks
The Healthy Eating Index (HEI) is a scoring metric developed by the U.S. Department of Agriculture (USDA) and the NCI to assess how well a person's diet conforms to the Dietary Guidelines for Americans. It evaluates the consumption of 13 dietary components, including both adequacy (foods to increase) and moderation (foods to decrease). The scores range from 0 to 100. An ideal overall HEI score of 100 reflects that the set of foods aligns with key dietary recommendations and dietary patterns published in the Dietary Guidelines.
Secondary Outcomes
- Change in Body Weight(Baseline and 12 weeks)
Investigators
Shiba Simon Bailey
Posdoctoral Fellow
University of South Carolina