Culturally-targeted Communication to Promote SARS-CoV-2 Antibody Testing in Saliva: Enabling Evaluation of Inflammatory Pathways in COVID-19 Racial Disparities
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 666
- 试验地点
- 2
- 主要终点
- Number (Percentage) of Participants Requested to Participate in Saliva-based SARS-CoV-2 Antibody Testing
研究概览
简要总结
This disparities-focused study seeks to evaluate communication strategies for better encouraging understanding and uptake of salivary SARS-CoV-2 antibody testing among African Americans residing in Flint, Michigan. This iteration will consider individuals recruited from the Flint Registry and assess willingness to participate in a drive-up saliva sample collection taking place at a central location in Flint, Michigan.
详细描述
African Americans develop and die from SARS-CoV-2 infection more than any other racial group in the United States, including in majority African American cities such as Flint, Michigan. Addressing these disparities may be aided by SARS-CoV-2 antibody testing. However, African Americans may be reluctant to partake in conventional antibody testing programs due to medical mistrust and experiences with racism. This study seeks to evaluate communication strategies for better encouraging understanding and uptake of salivary SARS-CoV-2 antibody testing. The central hypothesis is that African-Americans will be more receptive to antibody testing when benefits and limitations are communicated in a culturally effective manner. Our clinical trial aims are to 1) develop and compare effects of a general versus culturally-targeted video about antibody testing on African American and White Flint residents' antibody testing attitudes and uptake; 2) identify and compare effects of a general versus culturally-targeted video on activation of medical mistrust and racism-related cognition among African Americans when considering antibody testing. In collaboration with clinical and community partners, we have prepared and will evaluate general and culturally-targeted video tutorials about SARS-CoV-2 antibody testing. These brief videos will be distributed to the Flint community through the Flint Registry - a highly visible local health resource exchange. We will furnish an opportunity to engage salivary antibody screening and measure willingness to participate. In this study iteration, we will consider willingness to participate in a drive-up saliva sample collection that is taking place at a central location in Flint, Michigan.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Screening
- 盲法
- Single (Participant)
盲法说明
Participants will be unaware of their assignment to a general versus culturally targeted condition.
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •African American or White, 18 or older, and enrolled in the Flint Registry
排除标准
- •All who do not meet inclusion criteria.
结局指标
主要结局
Number (Percentage) of Participants Requested to Participate in Saliva-based SARS-CoV-2 Antibody Testing
时间窗: Immediately following didactic study portion and health communication randomization on day 1.
Number (Percentage) of participants who respond "yes" to be included in offer to participate in no cost SAR-CoV-2 salivary antibody test.
SARS-CoV-2 Antibody Testing Attitudes
时间窗: Immediately following didactic study portion and health communication randomization on day 1.
Submeasure of Theory of Planned Behavior Indicating extent of a favorable attitude SARS-CoV-2 towards antibody testing (Seven point Likert Rating, with higher scores indicating more favorable Attitudes).
SARS-CoV-2 Antibody Testing Normative Beliefs
时间窗: Immediately following didactic study portion and health communication randomization on day 1.
Sub-measure of Theory of Planned Behavior Indicating extent to which believes other people are favorable towards SARS-CoV-2 towards antibody testing (Seven point Likert Rating, with higher scores indicating stronger Normative Beliefs).
Number (Percentage) of Participants Who Requested Saliva-based SARS-CoV-2 Antibody Testing Participated in the Testing.
时间窗: 8 weeks from the day of consenting to participate in the salivary-based SARS-CoV-2 antibody testing
Number (Percentage) of participants that requested to participate in antibody testing who actually complete antibody testing.
Antibody Testing Perceived Behavioral Control
时间窗: Immediately following didactic study portion and health communication randomization on day 1.
Sub-measure of Theory of Planned Behavior Indicating Self Efficacy to Complete Antibody Testing (Seven point Likert Rating, with higher scores indicating greater Perceived Behavioral Control).
Antibody Testing Anticipatory Racism
时间窗: Immediately following didactic study portion and health communication randomization on day 1.
Extent to which participants believe that racism-related factors would diminish the value of SARS-CoV-2 antibody testing for self (Seven-point Likert rating, with higher scores indicating greater Anticipatory Racism).
Antibody Testing Intentions
时间窗: Immediately following didactic study portion and health communication randomization on day 1.
Sub-measure of Theory of Planned Behavior indicating Intentions to Complete Antibody Testing (Seven point Likert Rating, with higher scores indicating stronger screening Intentions).
次要结局
未报告次要终点
研究者
Todd Lucas
Principal Investigator
Michigan State University