Culturally-Targeted COVID-19 Communication and SARS-CoV-2 Antibody Testing Evaluation and Uptake

Not Applicable

Completed

Conditions: SARS-CoV2 Infection

Interventions: Behavioral: General SARS-CoV-2 Communication
Behavioral: Culturally Targeted SARS-CoV-2 Communication

Registration Number: NCT04957082

Lead Sponsor: Michigan State University

Brief Summary: This disparities-focused study seeks to evaluate communication strategies for better encouraging understanding and uptake of salivary SARS-CoV-2 antibody testing among African Americans residing in Flint, Michigan. This iteration will consider individuals recruited from the Flint Registry and assess willingness to participate in a drive-up saliva sample collection taking place at a central location in Flint, Michigan.

Detailed Description: African Americans develop and die from SARS-CoV-2 infection more than any other racial group in the United States, including in majority African American cities such as Flint, Michigan. Addressing these disparities may be aided by SARS-CoV-2 antibody testing. However, African Americans may be reluctant to partake in conventional antibody testing programs due to medical mistrust and experiences with racism. This study seeks to evaluate communication strategies for better encouraging understanding and uptake of salivary SARS-CoV-2 antibody testing. The central hypothesis is that African-Americans will be more receptive to antibody testing when benefits and limitations are communicated in a culturally effective manner. Our clinical trial aims are to 1) develop and compare effects of a general versus culturally-targeted video about antibody testing on African American and White Flint residents' antibody testing attitudes and uptake; 2) identify and compare effects of a general versus culturally-targeted video on activation of medical mistrust and racism-related cognition among African Americans when considering antibody testing. In collaboration with clinical and community partners, we have prepared and will evaluate general and culturally-targeted video tutorials about SARS-CoV-2 antibody testing. These brief videos will be distributed to the Flint community through the Flint Registry - a highly visible local health resource exchange. We will furnish an opportunity to engage salivary antibody screening and measure willingness to participate. In this study iteration, we will consider willingness to participate in a drive-up saliva sample collection that is taking place at a central location in Flint, Michigan.

Recruitment & Eligibility

Status: COMPLETED

Sex: All

Target Recruitment: 666

Inclusion Criteria

African American or White, 18 or older, and enrolled in the Flint Registry

Exclusion Criteria

All who do not meet inclusion criteria.

Study & Design

Study Type: INTERVENTIONAL

Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
African American Registry: General	General SARS-CoV-2 Communication	African American participants receive "general consumption" video information about SARS-CoV-2 antibody testing.
African American Registry: Culturally Targeted	Culturally Targeted SARS-CoV-2 Communication	African American participants receive culturally targeted video information about SARS-CoV-2 antibody testing.
White Flint Registry: General	General SARS-CoV-2 Communication	White participants receive "general consumption" video information about SARS-CoV-2 antibody testing.

Primary Outcome Measures

Name	Time	Method
Number (Percentage) of Participants Requested to Participate in Saliva-based SARS-CoV-2 Antibody Testing	Immediately following didactic study portion and health communication randomization on day 1.	Number (Percentage) of participants who respond "yes" to be included in offer to participate in no cost SAR-CoV-2 salivary antibody test.
SARS-CoV-2 Antibody Testing Attitudes	Immediately following didactic study portion and health communication randomization on day 1.	Submeasure of Theory of Planned Behavior Indicating extent of a favorable attitude SARS-CoV-2 towards antibody testing (Seven point Likert Rating, with higher scores indicating more favorable Attitudes).
SARS-CoV-2 Antibody Testing Normative Beliefs	Immediately following didactic study portion and health communication randomization on day 1.	Sub-measure of Theory of Planned Behavior Indicating extent to which believes other people are favorable towards SARS-CoV-2 towards antibody testing (Seven point Likert Rating, with higher scores indicating stronger Normative Beliefs).
Number (Percentage) of Participants Who Requested Saliva-based SARS-CoV-2 Antibody Testing Participated in the Testing.	8 weeks from the day of consenting to participate in the salivary-based SARS-CoV-2 antibody testing	Number (Percentage) of participants that requested to participate in antibody testing who actually complete antibody testing.
Antibody Testing Perceived Behavioral Control	Immediately following didactic study portion and health communication randomization on day 1.	Sub-measure of Theory of Planned Behavior Indicating Self Efficacy to Complete Antibody Testing (Seven point Likert Rating, with higher scores indicating greater Perceived Behavioral Control).
Antibody Testing Anticipatory Racism	Immediately following didactic study portion and health communication randomization on day 1.	Extent to which participants believe that racism-related factors would diminish the value of SARS-CoV-2 antibody testing for self (Seven-point Likert rating, with higher scores indicating greater Anticipatory Racism).
Antibody Testing Intentions	Immediately following didactic study portion and health communication randomization on day 1.	Sub-measure of Theory of Planned Behavior indicating Intentions to Complete Antibody Testing (Seven point Likert Rating, with higher scores indicating stronger screening Intentions).