Comparison of bispectral index(BIS) change and clinical signs of awakening during sugammadex reversal of neuromuscular block according to the depth of propofol-remifentanil anesthesia
- Conditions
- Not Applicable
- Registration Number
- KCT0006248
- Lead Sponsor
- Samsung Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 66
1) Patents who have American society of anesthesiologist physical status I to III
2) Patients who are planned to undergo elective major abdominal surgery using propofol-remifentanil anesthesia taking one hour or more.
1) Pediatric patient at or under 18.
2) Body Mass Index > 35 kg / m 2 or <18.5 kg / m 2
3) Severe liver disease
4) Severe kidney disease (GRF <30 or under hemodialysis)
5) Neuromuscular disease or mental illness
6) Those diagnosed with metabolic diseases
7) Drug addiction or alcohol addiction
8) Emergency surgery
9) Pregnant women or nursing women
10) People who have contraindications to muscle relaxants and sugammadex
- Patients who have allergies to drugs or have a history of hypersensitivity reactions, respiratory disease patients, arrhythmia patients
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical sign of arousal (eye opening, cough, spontaneous movements, response to simple commands, complete recovery)
- Secondary Outcome Measures
Name Time Method The change in BIS value after the sugammadex administration;The change in BIS-EMG value after the sugammadex administration;awake or recall during the surgery