NCT05988047已完成不适用
Analysis of CMTM6 Expression in Patients With Acute Myeloid Leukemia
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- T cell activation (FC)
研究概览
简要总结
In this study, we aim to investigate the expression of CKLF like MARVEL transmembrane domain containing 6 (CMTM6) in leukemia cells of patients with acute myeloid leukemia (AML). We will use peripheral blood samples and assess CMTM6 expression by flow cytometry and Western Blot.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age ≥ 18 years
- •primary diagnosis of acute myeloid leukemia
- •diagnosis results available
- •written informed consent
- •ability to understand the nature of the study and the study related procedures and to comply with them
排除标准
- •age < 18 years
- •lack of informed consent
结局指标
主要结局
T cell activation (FC)
时间窗: At primary diagnosis
T cell activation and cytokine production will be measured by flow cytometry
CMTM6 expression (FC)
时间窗: At primary diagnosis
CMTM6 expression on blasts/monocytes will be measured by flow cytometry
次要结局
- CMTM6 expression (WB)(At primary diagnosis)
研究者
Robert Zeiser
Professor
University of Freiburg
研究点 (1)
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