NCT00394108已完成不适用
Changes in Cerebrovascular Reactivity During Cognitive Activation After Cardiopulmonary Bypass: Relation With Intraoperative Embolic Load and Postoperative Neuropsychological Dysfunctions
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 66
- 试验地点
- 2
- 主要终点
- Neuropsychological status
研究概览
简要总结
The study aims to evaluate neuropsychological disorders in CABG patients. Measurements are performed 1 day before, 6 days, 6 months and 3-5 years after the surgery. The relation with cerebrovascular reactivity and embolic load (measured by transcranial Doppler Ultrasonography) is evaluated. Two surgery techniques (on- and off-pump CABG) are compared.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 69 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •CABG-patients (not urgent)
- •< 70 years old
- •Righthanded
排除标准
- •Neurological or psychiatric disease
- •Psychoactive medication
- •Valve operation
结局指标
主要结局
Neuropsychological status
时间窗: after 6 days, 6 months and 3-5 years
次要结局
- Relation with intra-operative embolic load
研究者
研究点 (2)
Loading locations...
相似试验
尚未招募
不适用
Research on the Relationship Between Cognitive Function Changes and Cerebrovascular Health in Patients With Coronary Heart DiseaseImageCoronary Heart DiseaseNCT05848934Nanjing University of Traditional Chinese Medicine100
已完成
不适用
Aerobic Exercise Training in Mild Cognitive Impairment StudyMild Cognitive ImpairmentNCT01146717University of Texas Southwestern Medical Center80
进行中（未招募）
2 期
Evaluating the Neurophysiologic and Clinical Effects of Single Dose Drug ChallengeFragile X SyndromeNCT05418049Children's Hospital Medical Center, Cincinnati45
已完成
不适用
Neural Mechanisms of Change During the Treatment of Alcohol Use Disorders With PrazosinAlcohol Use DisorderNCT01916941University of New Mexico36
已完成
早期 1 期
Neurophysiological and Acute Pharmacological Studies in FXS PatientsFragile X SyndromeNCT02998151Children's Hospital Medical Center, Cincinnati29