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Clinical Trials/NCT02259101
NCT02259101
Completed
N/A

A Randomized Controlled Trial of Cognitive Behavior Therapy for Insomnia With Persons Living With HIV/AIDS

Emory University1 site in 1 country34 target enrollmentNovember 2013
ConditionsInsomniaHIVAids

Overview

Phase
N/A
Intervention
Not specified
Conditions
Insomnia
Sponsor
Emory University
Enrollment
34
Locations
1
Primary Endpoint
Insomnia Symptoms
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

The proposed study will consist of a randomized controlled trial (RCT) comparing a known efficacious treatment for insomnia (CBT-I) to a sleep hygiene (SH) comparison condition.

Detailed Description

The purpose of this study is to test whether a group cognitive-behavioral treatment program for insomnia (CBT-I) will help adults diagnosed with HIV to improve the quantity (number of hours) and the quality of their sleep. The PI will compare adults who participated in the CBT-I program to adults who participated in a Sleep Hygiene group, a common treatment for insomnia. The PI will look at the overall quality of life, and number of hours and quality of sleep of adults who participated in the CBT-I program versus adults in the Sleep Hygiene group. Also, the PI will draw blood to compare how the body responds to medical illnesses between adults in the CBT-I program to adults in the Sleep Hygiene group.

Registry
clinicaltrials.gov
Start Date
November 2013
End Date
February 2016
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Amit Shahane

Assistant Professor

Emory University

Eligibility Criteria

Inclusion Criteria

  • English-speaking individuals
  • over the age of 18 years old with a diagnosis of HIV or AIDS who is receiving medical care at the Grady Health System's Infectious Disease Program (IDP)
  • study subjects must meet the criteria for primary or secondary insomnia as defined by the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition, Text Revision
  • must experience difficulty initiating or maintaining non-restorative sleep for at least l month (DSM- IV-TR)
  • the sleep disturbance causes clinically significant impairment or distress in important areas of functioning
  • sleep efficiency of less than 85%, sleep disturbances that occur three or more days per week, and sleep latency (i.e., time awake after sleep onset greater than 30 minutes)

Exclusion Criteria

  • current substance dependence (within the past six months)
  • active psychosis
  • Bipolar I and II disorders
  • neurocognitive impairment and/or a current diagnosis of dementia
  • lack of independent housing
  • previous participation in a CBT-I program
  • employment in a job requiring shift work that impairs the ability to establish a regular sleep schedule

Outcomes

Primary Outcomes

Insomnia Symptoms

Time Frame: baseline, up to 5 weeks post-intervention

Compare insomnia scores on the Insomnia Severity Index (questionnaire) between the CBT-I treatment condition vs. SH comparison condition.

Secondary Outcomes

  • Blood Sample(baseline, up to 5 weeks post-intervention)
  • Quality of Life(baseline, up to 5 weeks post-intervention)

Study Sites (1)

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