A New Prognostic Scoring System for Spontaneous Ruptured Hepatocellular

Completed

• Conditions: Rupture, Spontaneous

• Registration Number: NCT03504358
• Lead Sponsor: Huazhong University of Science and Technology

Brief Summary

Develop a new scoring system for HCC patients with tumor rupture.

Detailed Description

There has been no special prognostic scoring system for HCC patients with tumor rupture in the literature. In this work, we obtained all survival risk factors of ruptured HCC patients who underwent partial hepatectomy using multivariable Cox regression analysis. Furthermore, we develop and validate a new postoperative scoring system for patients with spontaneous HCC rupture based on the these results.

Study Timeline

• Study Start: 2005-01-01
• Primary Completion: 2015-05-01
• Study Completion: 2017-12-31
• Status Verified: 2018-04
• Study First Submitted: 2018-04-04
• Study First Submitted QC: 2018-04-12
• Last Update Submitted: 2018-04-12
• Study First Posted: 2018-04-20
• Last Update Posted: 2018-04-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 129

Inclusion Criteria

• Received partial hepatectomy; with Child A or B liver function.

Exclusion Criteria

• Without complete data；loss of follow-up; had reveived repeated transcatheter arterial chemoembolization before rupture; received non-radical resection.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Overall survival	3 years	Overall survival after partial hepatectomy

Secondary Outcome Measures

Name	Time	Method
Disease-free survival	3 years	Recurrence-free survival after partial hepatectomy