The Coronavirus Disease 2019 - Recovery Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 536
- 试验地点
- 29
- 主要终点
- Disability-free survival
研究概览
简要总结
Patients who are critically ill with COVID-19 requiring life support in an intensive care unit (ICU) have increased risk of morbidity and mortality. Currently the ICU community does not know what effect the disease, the ICU admission, physiotherapy interventions and life support have on their long-term quality of life and whether they can return to their pre-illness level of function following ICU.
COVID-Recovery will describe the physiotherapy interventions delivered to critically ill patients with COVID-19. In survivors, COVID-Recovery will utilise telephone follow-up of ICU survivors to assess disability-free survival and quality of life at 6 months after ICU admission. Additionally, COVID-Recovery will identify if there are predictors of disability-free survival. COVID-Recovery will aim to select up to 300 patients diagnosed with COVID-19 from ICUs in Australia. If they survive to hospital discharge, patients will be invited to receive a telephone questionnaire at 6 months after the ICU admission that aims to assess their long-term outcomes, including physical, cognitive and emotional function, quality of life, and whether they have been able to return to work following ICU discharge.
To describe the experience of critical illness in survivors of COVID-19 and their family members.
To explore and describe functional recovery, respiratory system function and respiratory health morbidity up to 6 months after ICU admission in persistently critically ill adults with COVID-19
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 17 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •COVID-19 patients who have been admitted to ICU for > 24 hours
- •Patients aged over 17 years
- •Persistent critical illness cohort
- •An ICU admission of at least 10 consecutive days
排除标准
- •Previous enrolment in this study in a prior ICU admission
结局指标
主要结局
Disability-free survival
时间窗: 6 months
a composite measure of WHODAS 2.0 - 12 level and hospital survival
Physiotherapy intervention
时间窗: During the ICU stay until 3 months
The physiotherapy interventions provided to patients with COVID-19 admitted to the ICU and health outcomes
次要结局
- Cognitive function(6 months)
- The reported barriers to delivering physiotherapy interventions(During the ICU stay until 28 days)
- Anxiety and depression(6 months)
- Adverse events during physiotherapy interventions(During the ICU stay until 28 days)
- Health status(6 months)
- Global function(6 months)
- Proportion of patients with COVID-19 who received physiotherapy in ICU(During the ICU stay until 28 days)
- Phenomenological data of the patient and family experience(6 months)
- Screening for post-traumatic distress(6 months)
- Work Status(6 months)