Physiological Factors That Influence Maintenance of Lifestyle Changes and Weight Loss - a Cross-sectional Study

Completed

• Conditions: Obesity; Overweight
• Interventions: Behavioral: Intensive Lifestyle Intervention

• Registration Number: NCT01997034
• Lead Sponsor: University of Copenhagen

Brief Summary

In Denmark and the western world, there is an increasing prevalence of obesity probably due to a combination of inadequate daily physical activity and a high energy intake. One approach to achieve weight loss and change life style is to participate in an intensive supervised prolonged life style modification course. The immediate effect is often positive, but over time the overall effect is limited as the majority will not maintain weight loss and a changed life style.

The purpose of this study is therefore to characterize the physiological factors that determine/influence the capacity to maintain weight loss and a healthy lifestyle after a prolonged lifestyle intervention.

The investigators have the following research questions:

1. Are there physiological traits and characteristics that mediate better adherence to lifestyle changes and weight loss?

2. Does the adaptation in muscle oxidative capacity after lifestyle intervention predict success in maintaining weight loss and lifestyle changes?

3. How does gender and age influence the capacity to maintain the lifestyle induced adaptation in muscle and adipose tissue and maintaining weight loss?

The study design is cross-sectional and will be based on a lifestyle intervention, as it is practiced in a real life setting at Ubberup folk high school. The investigators will recruit former participants of this lifestyle style intervention. 50 % who maintained a weight loss and a healthy life style and 50 % who did not.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-11
• Study First Submitted: 2013-11-21
• Study First Submitted QC: 2013-11-26
• Study First Posted: 2013-11-27
• Primary Completion: 2015-12
• Study Completion: 2015-12
• Status Verified: 2016-01
• Last Update Submitted: 2016-01-29
• Last Update Posted: 2016-02-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Former participants of Ubberup Folk High School

Exclusion Criteria

• Gastric Bypass Surgery or Gastric Banding

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Intensive Lifestyle Intervention	Intensive Lifestyle Intervention	Former participants of Ubberup Folk High Schools intensive lifestyle intervention programme.

Primary Outcome Measures

Name	Time	Method
Total Body weight	0-14 years after the intervention is completed

Secondary Outcome Measures

Name	Time	Method
Anthropometry	0-14 years after the intervention is completed	Body composition measured by dual x-ray absorptiometry or bio-impedance, height, weight, waist circumference.
Maximal Oxygen Consumption	0-14 years after the intervention is completed
Maximal fat oxidation	0-14 years after the intervention is completed	Respiratoric Exchange Ratio (RER) is measured during an incremental cycling test and maximal fat oxidation is calculated

Trial Locations

Locations (1)

University of Copenhagen, Department of Biomedical Sciences; 🇩🇰 Copenhagen, Denmark