Time of Postpartum Hemoglobin Assessment and Blood Loss During Delivery

Completed

• Conditions: Hemorrhage, Postpartum
• Interventions: Procedure: Blood Draw

• Registration Number: NCT03233607
• Lead Sponsor: Columbia University

Brief Summary

This is a prospective cohort study of patients delivering at Columbia University Medical Center/ Allen Hospital. For the primary research question, the investigators will compare the change in maternal hemoglobin from postpartum day 1 to day 2 and also determine correlation with estimation of blood loss (EBL) and quantitative blood loss (QBL).

Detailed Description

Postpartum hemorrhage is a leading cause of maternal mortality and morbidity worldwide. Early intervention is dependent on care providers ability to accurately estimate ongoing blood loss. Studies in the past have shown that obstetricians and midwives tend to overestimate blood loss when the lost volumes are small while tend to underestimate by as much as 40 to 50 percent when a large volume of blood is lost.

Multiple studies have shown that routine hemoglobin assessment in postpartum patients after uneventful delivery either vaginal or via cesarean section, is not necessary. This leads to increased cost of care without any added benefit and causes inconvenience to the patients. However knowing how imprecise blood loss estimation can be it is reasonable to screen women for anemia prior to discharge.

Study Timeline

• Study First Submitted: 2017-07-26
• Study First Submitted QC: 2017-07-26
• Study First Posted: 2017-07-28
• Study Start: 2018-03-20
• Primary Completion: 2019-01-04
• Status Verified: 2019-04
• Study Completion: 2019-04-23
• Last Update Submitted: 2019-04-23
• Last Update Posted: 2019-04-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

All antepartum patients receiving prenatal care at the Broadway Practice and plan to deliver at Allen Hospital in NYC.

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Exclusion Criteria

Patients who gave consent to participate in the study but did not deliver at Allen hospital.

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Antepartum Patients	Blood Draw	Includes antepartum patients receiving prenatal care at the Broadway Practice who plan to deliver at Allen Hospital in New York City (NYC). On postpartum day 1 and day 2, a sample of blood will be drawn in the morning for hemoglobin and hematocrit estimation.

Primary Outcome Measures

Name	Time	Method
Correlation of maternal hemoglobin to EBL	Up to 2 days after delivery	Maternal hemoglobin will be measured to assess correlation to visually estimated blood loss
Correlation of maternal hemoglobin to QBL	Up to 2 days after delivery	Maternal hemoglobin will be measured to assess correlation to quantified blood loss
Change in maternal hemoglobin	Day 1 and Day 2	Maternal hemoglobin will be measured on postpartum day 1 to day 2

Trial Locations

Locations (1)

Columbia University Irving Medical Center; 🇺🇸 New York, New York, United States