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Clinical Trials/NCT06018311
NCT06018311
Active, Not Recruiting
N/A

A Pilot Feasibility Study of a Culturally Adapted Partnered Strength Training Intervention for Hispanic Cancer Survivors and Their Caregivers

University of Arizona1 site in 1 country58 target enrollmentNovember 1, 2023

Overview

Phase
N/A
Intervention
Not specified
Conditions
Not specified
Sponsor
University of Arizona
Enrollment
58
Locations
1
Primary Endpoint
Feasibility measured by enrollment rate
Status
Active, Not Recruiting
Last Updated
last month

Overview

Brief Summary

The purpose of this study is to determine the feasibility and effects of an adapted Exercising Together, a partnered resistance training program, on the physical and mental health of prostate cancer survivors and their informal caregiver. The Exercising Together program is designed to promote teamwork during supervised group exercise classes delivered remotely through videoconferencing software. The intervention period will be 3-months with a 3-month follow-up.

Registry
clinicaltrials.gov
Start Date
November 1, 2023
End Date
December 31, 2026
Last Updated
last month
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Inclusion Criteria (Survivor only):
  • Self-identifies as Hispanic
  • Histologically confirmed prostate cancer diagnosis (self-report)
  • Completed primary treatment at least 6 weeks prior at time of enrollment
  • Has an identified caregiver in any relationship role (e.g., spouse, sibling, parent, friend) who can participate with them.
  • Inclusion Criteria (Caregivers):
  • 1\. Identifies as an individual (e.g., family member or friend) who provides unpaid care or support to a participating prostate cancer survivor.
  • Inclusion Criteria (Survivors and Caregivers):
  • ≥18 years of age
  • Understands (ability to read and speak) English or Spanish and able to provide informed consent

Exclusion Criteria

  • Cognitive difficulties that preclude answering the survey questions, participating in the exercise classes or performance tests, or providing informed consent as determined by the professional opinion of the Principal Investigator
  • A medical condition, movement or neurological disorder, or medication use that contraindicates participation in moderate intensity exercise or poses a significant safety concern/risk for the well-being of the participant (e.g., declared pregnancy, poorly controlled diabetes, recent cardiac event, neuromuscular disease, untreated orthostatic hypertension, recent surgery, acute hernia, acute rheumatoid arthritis, severe memory disorders, severe balance disorder, severe hearing or vision impairment)
  • Knowingly unable to attend \>75% of the intervention classes due to conflict with the designated time of day, days of the week, and/or location for the exercise class which they initially enrolled
  • Incapable of providing informed consent, answering survey questions, participating in the intervention, and following directions during performance testing when English or Spanish language is used
  • Unable to be in the same location with participating member during remote exercise classes and performance testing and/or insufficient internet connectivity to support required videoconferencing software
  • Inclusion Criteria (Survivor only):
  • Histologically confirmed cancer diagnosis (self-report)
  • Completed primary treatment at least 6 weeks prior at time of enrollment
  • Has an identified caregiver in any relationship role (e.g., spouse, sibling, parent, friend) who can participate with them.
  • Inclusion Criteria for Caregivers remains the same as Phase 1 Exclusion Criteria remain the same as Phase 1

Outcomes

Primary Outcomes

Feasibility measured by enrollment rate

Time Frame: 3 months

Will be determined as the enrollment rate- the number of dyads enrolled out of those approached and eligible using descriptive statistics.

Implementation Success - composite measure of acceptability, appropriateness, and feasibility.

Time Frame: 3 months

Implementation success is a composite measure that will be measured by a single questionnaire that will determine the extent to which the intervention is considered acceptable, appropriate, and feasible. The single questionnaire will consist of 3 measures that will be summed into one final score, The Acceptability of Intervention Measure (AIM), Intervention Appropriateness Measure (IAM), and Feasibility of Intervention Measure (FIM). Responses from AIM, IAM, and FIM are summary scored with a possible range of 12-60; higher scores indicate greater acceptability, appropriateness, and feasibility.

Appropriateness measured by retention rate

Time Frame: 3 months

Will be determined as the retention rate- calculated as the number of dyads completing the study versus consented using descriptive statistics.

Acceptability measured by adherence to intervention

Time Frame: 3 months

Acceptability will be measured by adherence to the intervention calculated as the total number of classes attended divided by the total possible schedule the patient could attend using descriptive statistics.

Secondary Outcomes

  • Physical activity(Physical activity will be measured over a 6 month period. It will be measured at baseline, 3 months, and 6 months.)
  • Health-Related Quality of Life (HR-QOL) for the caregiver(HR-QOL will be measured over a 6 month period. It will be measured at baseline, 3 months, and 6 months.)
  • Health-Related Quality of Life (HR-QOL) for the survivor(HR-QOL will be measured over a 6 month period. It will be measured at baseline, 3 months, and 6 months.)
  • Relationship Health(Relationship Health will be measured over a 6 month period. It will be measured at baseline, 3 months, and 6 months.)
  • Objective Physical Function(Objective Physical Function will be measured over a 6 month period. It will be measured at baseline, 3 months, and 6 months.)

Study Sites (1)

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