Interest of Impedancemetry in Monitoring Hydration and Hyponatremia During Subarachnoid Hemorrhages

Recruiting

• Conditions: Subarachnoid Hemorrhage (SAH)

• Registration Number: NCT06646484
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

Subarachnoid hemorrhage (SAH) is a rare and serious form of stroke, mainly linked to the rupture of an intracranial aneurysm responsible for bleeding into the meningeal spaces.

The main late serious complication is delayed cerebral ischemia (DCI), resulting in the appearance of new neurological deficits.

Prevention of ICR involves in particular maintaining euvolemia, and early treatment of hyponatremia, itself dependent on the level of volume.

Evaluation of water status and sodium balance is therefore essential. This assessment is complicated and relies on indirect parameters, both clinical and biological.

Impedancemetry, making it possible to measure water volumes and sodium load, could be an aid in the management of blood volume and sodium intake.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-10-11
• Study First Submitted QC: 2024-10-16
• Study First Posted: 2024-10-17
• Study Start: 2024-12-30
• Status Verified: 2025-01
• Last Update Submitted: 2025-01-10
• Last Update Posted: 2025-01-13
• Primary Completion: 2025-12-30
• Study Completion: 2026-01-21

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Adult man, woman
• Hospitalized following Subarachnoid Hemorrhage within 72 hours of bleeding
• Admitted to the neurological intensive care unit for less than 48 hours
• Being able to understand the ins and outs of the study
• Having expressed his non-opposition

Exclusion Criteria

• Patients under legal protection
• Pregnancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hydration measurements	Every 48 hours during the mean 21 days of stay in the neurological ICU.	The level of hydration is quantified by the indicator "Hydration of non-fat mass in%" using the impedancemetry. Threshold values for hydration indices are specific to the measurement performed on the patient and depend on their age, gender and body composition data.

Trial Locations

Locations (1)

Hospices Civils de Lyon. Neurological ICU; 🇫🇷 Lyon, France