COMPARISON OF NALBUPHINE AND BUPRENORPHINE ADDED TO 0.5%LEVOBUPIVACAINE TO PRODUCE NERVEBLOCK FOR HAND SURGERIES
Phase 2
- Conditions
- Health Condition 1: M808- Other osteoporosis with current pathological fractureHealth Condition 2: M628- Other specified disorders of muscle
- Registration Number
- CTRI/2021/09/036728
- Lead Sponsor
- sapthagiri institute of medical sciences and research center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients aged between 18 - 60 years
2.Both gender
3.ASA 1 and ASA 2 patients
4.Weight between 40kg -80kg (BMI b/w 23-35kg/m2)
5.Elective upper limb orthopedic surgeries of 1-4hour duration
Exclusion Criteria
1.Patient refusal for regional anaesthesia
2.Allergic to study drug and local anesthetic
3.Patients who have arrhythmia,heart failure,renal failure,liver failure. •
4.H/o Autonomic dysfunction (Diabetic neuropathy)
•H/o seizure disorder
•H/o Psychiatric illness
•With severe broncho pulmonary diseases
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the efficacy (onset, duration, and post-operative <br/ ><br>analgesia) of adding nalbuphine versus buprenorphine to levobupivacaineTimepoint: onset of sensory and motor block by pin prick test and modified bromage 2 points score at <br/ ><br>every 3minutes interval for initial 30 minutes.
- Secondary Outcome Measures
Name Time Method To compare amongst these study drugs-The hemodynamic ParametersTimepoint: Haemodynamic parameters: HR,SBP,DBP,MAP,RR,SPO2 at 5minutes interval till the end of <br/ ><br>surgery.