Assessment of Prokinetic Effects of Erythromycin in Emergency Patients With a Full Stomach

Completed

• Conditions: Emergency Surgery; Full Stomach

• Registration Number: NCT02296866
• Lead Sponsor: Lionel Bouvet

Brief Summary

The aims of the study is to assess whether the intravenous infusion of 3 mg/kg erythromycin has a significant gastrokinetic effect leading to empty the stomach in less than 90 minutes in non-fasting patients undergoing emergency trauma surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-09
• Primary Completion: 2014-11
• Study Completion: 2014-11
• Study First Submitted: 2014-11-18
• Study First Submitted QC: 2014-11-19
• Study First Posted: 2014-11-20
• Status Verified: 2014-12
• Last Update Submitted: 2014-12-26
• Last Update Posted: 2014-12-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 28

Inclusion Criteria

• Emergency surgery for trauma
• ASA 1 and 2 patients
• Full stomach (antral area > 550 mm²)
• Adult patients

Exclusion Criteria

• No contraindication to erythromycin
• Extreme emergency surgery (time frame < 90 min between arrival in the service and the start of the surgery)
• gastroparesis or pathology associated with gastroparesis

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ultrasonographic measurement of antral area	30 minutes and immediately before erythromycin infusion, and 30, 60 and 90 min after the start of erythromycin infusion

Trial Locations

Locations (1)

Hopital Edouard Herriot; 🇫🇷 Lyon, France