JPRN-UMIN000003713已完成2 期
A phase II multicenter study of mycophenolate mofetil for acute graft-versus-host disease (aGVHD) prophylaxis in allogeneic hematopoietic stem cell transplantation from related donors - MMF for aGVHD prophylaxis in allo-HSCT from related donors.
Grant for anticancer project from Ministry of Health, Welfare, and Labor of Japan.0 个研究点目标入组 19 人开始时间: 2010年6月4日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 19
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 16years-old 至 70years-old（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •(1)Major organ dysfunction(non-myeloablative SCT): (a)Ejection fraction: <40% (b)Pulmonary function test: %VC<30%, FEV1.0% <40%, or SaO2 <90% on room air (c)Serum creatinine: >2.0mg/dl (d)Liver function: total bilirubin >2.0mg/dl, AST or ALT >3 x UNL, or patients with chronic active hepatitis or liver cirrhosis (2)Poorly controlled hypertension (3)HIV antibody positivity (4)Uncontrolled active infection (5)Uncontrolled CNS invasion (6)Pregnant, nursing or possibly pregnant woman (7)Patients with severe mental disorder who are likely unable to participate in the study (8)Known hypersensitivity or allergy to any of the drugs in the conditioning regimen of this transplant, or drugs used for GVHD prophylaxis (9)No indication for this study as judged by physician in charge.
研究者
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