Epidemiology of Occult Hepatitis C Virus Infection in Patients Born Before 1969 in the Hospital Setting: a Spontaneous Opportunistic Screening Initiative.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 4,000
- 主要终点
- prevalence of antibodies against hepatitis C virus in cohort population
研究概览
简要总结
The goal of this monocentric prospective observational study is to evaluate the prevalence of unknown hepatitis C virus chronic infection in general population born before january 1st 1968 in Italy.
The main questions it aims to answer are:
what is the prevalence of hepatits C virus infection in general population born before January 1st, 1968? What rare the characteristics of these patients compared to the general population? What is the prevalence of patients tested HCV positive who are referred to the Hepatology Outpatient Clinic for further evaluation? What is the prevalence of patients with HCV infection detected during the study and treated with direct antiviral agents during follow up?
Participants will be tested with a point of care screening test (Meridian, Bioscience) able to detect anti-HCV antibodies to detect the presence of antibodies against HCV.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 54 Years 至 120 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients born before January 1st 1968 who lived in Italy referred to any departments of the Policlinico A. Gemelli
排除标准
- •Patients born after january 1st 1968
- •Known infection of hepatitis C virus
- •Previous treatment against hepatitis C virus
结局指标
主要结局
prevalence of antibodies against hepatitis C virus in cohort population
时间窗: 24 months
Evaluation of prevalence of antibodies against HCV in patients referred to any department of Policlinico Gemelli born before January 1st 1968
次要结局
- Prevalence of patients with a confirmed chronic HCV infection who are referred to Hepatology Outpatient clinic(24 months)
- Characteristics of population(24 months)
- Prevalence of patients with a confirmed chronic HCV infection who are treated with direct antiviral agents(24 months)
研究者
Ponziani Francesca Romana
Dr.
Fondazione Policlinico Universitario Agostino Gemelli IRCCS