Kidney Histopathology After COVID-19 and SARS-CoV-2 Vaccination
- Conditions
- Covid19Vaccination Reaction
- Registration Number
- NCT05043168
- Lead Sponsor
- University of Giessen
- Brief Summary
The study aims to summarize kidney histopathological findings in patients with coronavirus disease 2019 (COVID-19) and post-severe acute respiratory syndrome-coronavirus-type 2 (SARS-CoV-2) vaccination.
- Detailed Description
The SARS-CoV-2 pandemic has had substantial global morbidity and mortality. While COVID-19 is most commonly characterized as a respiratory illness, extrapulmonary manifestations are a prominent part its clinical spectrum. Kidney disease is a common finding in COVID-19, and has also been rarely described after SARS-CoV-2 vaccination. The main objective of this study is to summarize kidney histopathological findings in patients with COVID-19 and post-SARS-COV-2 vaccination, in whom native kidney biopsy was performed and samples were obtained by the Nephropathology Section, Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 42
- being diagnosed with COVID-19 when kidney biopsy was performed
- history of recent homologous or heterogenous vaccine regimen comprising either vector-based vaccines or messenger ribonucleic acid-based vaccines
- Patient refuses participation
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Frequency of histopathologically confirmed glomerular and tubulointerstitial diseases Kidney biopsy obtained during COVID-19 disease and up to 3 months after SARS-CoV-2 vaccination
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Clinic Giessen and Marburg - Campus Giessen
🇩🇪Giessen, Hessen, Germany