Effects of knee bracing on articular contact forces in people with knee osteoarthritis and varus malalignment

Australian Government: Commonwealth Innovation Connection Grant0 个研究点目标入组 30 人开始时间: 2019年4月26日最近更新: 2020年5月4日

适应症

试验速览

暂无简介。

•Inclusion criteria are based on the American College of Rheumatology clinical and radiographic criteria for knee osteoarthritis
•-Age greater than or equal to 50 years;
•-Report knee pain on most days of the past month for greater than 3 months;
•-Pain on most days (5-7 days/week or 20-30 days/month) in the last month;
•-Report a minimum pain score of 4 on an 11-point numeric rating scale during walking over the previous week;
•-Willing to wear a knee brace during daily activities, every day for 8 weeks;
•-Able to travel to undergo x-ray (if required) / MR examinations, and to attend the Centre for Health, Exercise and Sports Medicine (CHESM) human movement lab at the University of Melbourne for testing;
•-Radiographic medial tibiofemoral joint osteoarthritis*;
•*Specific inclusion criteria based on a posteroanterior weight-bearing radiograph are i) Kellgren/Lawrence grade 2 or more; ii) anatomic axis angle of less than 181 degrees for females or less than 183 degrees for males, indicating varus alignment based on mechanical axis values using the sex-specific regression equation ; iii) medial tibiofemoral joint narrowing grade greater than lateral tibiofemoral joint narrowing grade; iv) medial compartment osteophyte grade greater than or equal to lateral compartment osteophyte grade.

•-Knee or hip replacement on affected side or high tibial osteotomy;
•-Any knee surgery including arthroscopes in the past 6 months;
•-Have a body mass index greater than or equal to 36 kg/m2 (due to difficulties in three-dimensional gait analysis);
•-Awaiting or planning any back or lower-limb surgery within the next 3 months;
•-Plans to see an orthopaedic surgeon about knee within the next 8 weeks;
•-Current or past (within 3 months) oral or intra-articular corticosteroid use;
•-Systemic arthritic conditions;
•- Work restrictions of other commitments that would restrict wearing a knee brace during daily activities;
•-Current (or within past 6 months) muscular, joint or neurological condition;
•-Current (or within past 6 months), or intention to use with the next 8 weeks, a knee brace, walking stick or gait aid;
•-Absolute contraindications to MR imaging

发起方

Australian Government: Commonwealth Innovation Connection Grant