Effects of knee bracing on articular contact forces in people with knee osteoarthritis and varus malalignment

Australian Government: Commonwealth Innovation Connection Grant0 sites30 target enrollmentApril 26, 2019

Overview

No summary available.

Registry

who.int

Start Date

April 26, 2019

End Date

January 3, 2020

Last Updated

5 years ago

Study Type

Interventional

Sex

All

Sponsor

Australian Government: Commonwealth Innovation Connection Grant

•Inclusion criteria are based on the American College of Rheumatology clinical and radiographic criteria for knee osteoarthritis
•\-Age greater than or equal to 50 years;
•\-Report knee pain on most days of the past month for greater than 3 months;
•\-Pain on most days (5\-7 days/week or 20\-30 days/month) in the last month;
•\-Report a minimum pain score of 4 on an 11\-point numeric rating scale during walking over the previous week;
•\-Willing to wear a knee brace during daily activities, every day for 8 weeks;
•\-Able to travel to undergo x\-ray (if required) / MR examinations, and to attend the Centre for Health, Exercise and Sports Medicine (CHESM) human movement lab at the University of Melbourne for testing;
•\-Radiographic medial tibiofemoral joint osteoarthritis\*;
•\*Specific inclusion criteria based on a posteroanterior weight\-bearing radiograph are i) Kellgren/Lawrence grade 2 or more; ii) anatomic axis angle of less than 181 degrees for females or less than 183 degrees for males, indicating varus alignment based on mechanical axis values using the sex\-specific regression equation ; iii) medial tibiofemoral joint narrowing grade greater than lateral tibiofemoral joint narrowing grade; iv) medial compartment osteophyte grade greater than or equal to lateral compartment osteophyte grade.

•\-Knee or hip replacement on affected side or high tibial osteotomy;
•\-Any knee surgery including arthroscopes in the past 6 months;
•\-Have a body mass index greater than or equal to 36 kg/m2 (due to difficulties in three\-dimensional gait analysis);
•\-Awaiting or planning any back or lower\-limb surgery within the next 3 months;
•\-Plans to see an orthopaedic surgeon about knee within the next 8 weeks;
•\-Current or past (within 3 months) oral or intra\-articular corticosteroid use;
•\-Systemic arthritic conditions;
•\- Work restrictions of other commitments that would restrict wearing a knee brace during daily activities;
•\-Current (or within past 6 months) muscular, joint or neurological condition;
•\-Current (or within past 6 months), or intention to use with the next 8 weeks, a knee brace, walking stick or gait aid;