Knee bracing for medial arthritis of the knee

Not Applicable

Completed

• Conditions: Knee Osteoarthritis; Varus Malalignment; Musculoskeletal - Osteoarthritis; Physical Medicine / Rehabilitation - Physiotherapy

• Registration Number: ACTRN12619000622101
• Lead Sponsor: Australian Government: Commonwealth Innovation Connection Grant

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-04-26
• Study Completion: 2020-01-03
• Last Update Posted: 4 May 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Inclusion criteria are based on the American College of Rheumatology clinical and radiographic criteria for knee osteoarthritis

-Age greater than or equal to 50 years;
-Report knee pain on most days of the past month for greater than 3 months;
-Pain on most days (5-7 days/week or 20-30 days/month) in the last month;
-Report a minimum pain score of 4 on an 11-point numeric rating scale during walking over the previous week;
-Willing to wear a knee brace during daily activities, every day for 8 weeks;
-Able to travel to undergo x-ray (if required) / MR examinations, and to attend the Centre for Health, Exercise and Sports Medicine (CHESM) human movement lab at the University of Melbourne for testing;
-Radiographic medial tibiofemoral joint osteoarthritis*;
*Specific inclusion criteria based on a posteroanterior weight-bearing radiograph are i) Kellgren/Lawrence grade 2 or more; ii) anatomic axis angle of less than 181 degrees for females or less than 183 degrees for males, indicating varus alignment based on mechanical axis values using the sex-specific regression equation ; iii) medial tibiofemoral joint narrowing grade greater than lateral tibiofemoral joint narrowing grade; iv) medial compartment osteophyte grade greater than or equal to lateral compartment osteophyte grade.

Exclusion Criteria

-Knee or hip replacement on affected side or high tibial osteotomy;
-Any knee surgery including arthroscopes in the past 6 months;
-Have a body mass index greater than or equal to 36 kg/m2 (due to difficulties in three-dimensional gait analysis);
-Awaiting or planning any back or lower-limb surgery within the next 3 months;
-Plans to see an orthopaedic surgeon about knee within the next 8 weeks;
-Current or past (within 3 months) oral or intra-articular corticosteroid use;
-Systemic arthritic conditions;
- Work restrictions of other commitments that would restrict wearing a knee brace during daily activities;
-Current (or within past 6 months) muscular, joint or neurological condition;
-Current (or within past 6 months), or intention to use with the next 8 weeks, a knee brace, walking stick or gait aid;
-Absolute contraindications to MR imaging

Study & Design

• Study Type: Interventional
• Study Design: Not specified