Evaluating the efficacy of 0.25% Sodium Hypochlorite and 0.2% Chlorhexidine Digluconate as pocket irrigants and adjuncts to scaling and root planing in retarding the recolonization rates of Aggregatibacter Actinomycetemcomitans and Porohyromonas Gingivalis in stage II Grade B Periodontitis patients-A Randomized Controlled trial.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- reduced numbers of micro-organisms checked at baseline, i.e. aggregatibacter actenomycetemcomitans and Porphyromonas gingivalis.
研究概览
简要总结
Patients suffering from stage II grade B periodontitis will be selected from the outpatient department of Periodontics of the Institution.
Clinical parameters recorded will include:
Plaque Index (PI) by Sillness and Loe,
Gingival Index (GI) by Loe and Sillness,
Gingival Bleeding Index by Ainamo & Bay,
Pocket probing depth (PPD) recorded with an UNC 15 probe.
All the clinical parameters will be measured at baseline and 60th day.
Subgingival samples are collected at baseline and on the 60th day for all the patients. All patients undergo scaling and root planing. Patients will be randomly allocated to the two experimental and control groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 79.00 Year(s)（—）
- 性别
- All
入选标准
- •Signs of gingival inflammation.
- •Bleeding on probing.
排除标准
- •Antibiotics within 3 months prior to sample collection.
- •Pregnant and lactating women.
- •Tobacco users.
- •Presence of diabetes or other systemic illnesses.
结局指标
主要结局
reduced numbers of micro-organisms checked at baseline, i.e. aggregatibacter actenomycetemcomitans and Porphyromonas gingivalis.
时间窗: The sample to evaluate the above will be collected at baseline and 60th day.
次要结局
- Plaque Index (PI) ,(Gingival Index (GI),)
研究者
Ankitha S
Sharavathi Dental College