Femoral Blockade and Low-dose Spinal Anesthesia in Outpatient Knee Arthroscopy

Phase 4

Completed

• Conditions: Meniscus Lesion
• Interventions: Drug: Femoral blockade; Drug: Intrathecal anesthesia

• Registration Number: NCT02322372
• Lead Sponsor: Ankara University

Brief Summary

The investigators of the current study aimed to evaluate the effect of spinal anesthesia with low dose bupivacaine combined with femoral blockade on duration of anesthesia and time of first analgesic requirement during postoperative period

Detailed Description

Fifty patients undergoing arthroscopic meniscus repair were included to the current study.

The patients were allocated to two groups as the spinal anesthesia with conventional dose of heavy bupivacaine or spinal anesthesia with low dose heavy bupivacaine combined with femoral blockade.

Blood pressures and heart rates were recorded at the beginning, at the 0th minute following femoral block, at the 0th minute and in two-minute intervals following spinal anesthesia for 20 minutes and in five-minute intervals till the end of surgery.

The sensorial block and motor block in both extremities were recorded in two-minute intervals following spinal anesthesia and in five-minute intervals till the end of surgery The time of sensorial blockade to reach T12, maximum level of sensorial blockade level and the time to reach maximum level of sensorial blockade and the time for regression of sensorial blockade to L2, the time for regression of motor blockade were recorded.

Study Timeline

• Study Start: 2014-07
• Primary Completion: 2014-12
• Study Completion: 2014-12
• Study First Submitted: 2014-12-13
• Study First Submitted QC: 2014-12-22
• Study First Posted: 2014-12-23
• Status Verified: 2015-02
• Last Update Submitted: 2015-02-15
• Last Update Posted: 2015-02-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• ASA I-II patients aged between 25-65 undergoing arthroscopic meniscus repair

Exclusion Criteria

• Contraindications to regional anesthesia (coagulopathy, severe aortic stenosis, sever mitral stenosis, increased intracranial pressure, severe hypovolemia, presence of infection on the site of injection)
• Presence of previous spinal surgery
• Presence of diabetes mellitus
• Presence of neurological disturbance
• Uncooperated patients, patients not accepting to participate the study
• Allergy to study drugs
• ASA II-IV patients, BMI >38, Height < 150 cm and >190 cm

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Group F	Femoral blockade	Ultrasound-guided femoral blockade with 15 mL of bupivacaine 0.5% diluted in 15 mL saline was performed in supine position. Then the patient was turned to lateral decubitus position with the operated extremity on dependant position and intrathecal injection of heavy bupivacaine 1 mL (5 mg) was administered from L3-L4 intervertebral space at a rate of 1 mL/20 second. .
Group S	Intrathecal anesthesia	The patient was turned to lateral decubitus position with the operated extremity on dependant position and intrathecal injection of heavy bupivacaine 2 mL (10 mg) was administered from L3-L4 intervertebral space at a rate of 1 mL/20 second.

Primary Outcome Measures

Name	Time	Method
Time of sensorial block to regress L2	24 hours

Secondary Outcome Measures

Name	Time	Method
Time of first analgesic requirement	24 hours

Trial Locations

Locations (1)

Ankara University Medical School Anesthesiology and ICU Department; 🇹🇷 Ankara, Turkey