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The Evicel Post-Authorization Surveillance Study

Completed
Conditions
Peripheral Vascular Disease
Hemorrhage
Interventions
Biological: EVICEL ™ Fibrin Sealant (Human)
Registration Number
NCT01158261
Lead Sponsor
Ethicon, Inc.
Brief Summary

The objective of this non-interventional Post Authorisation Safety Surveillance (PASS) study is to observe the clinical safety performance of EVICEL when used as suture support for haemostasis in vascular surgery.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
300
Inclusion Criteria
  • Subjects, 18 years or older, requiring elective, primary or repeat vascular procedures with at least one end-to-side anastomosis to the femoral artery or to an upper extremity artery
  • EVICEL Fibrin Sealant is used as an adjunct to obtain haemostasis at a target anastomosis/es
  • Subjects must be willing to and capable of participating in the study, and provide written informed consent
Exclusion Criteria
  • Subjects with known intolerance to blood products
  • Subjects unwilling to receive blood products
  • Subjects with any intra-operative findings that may preclude the use of a fibrin sealant to control suture line anastomotic bleeding
  • Subject participating in another study with an investigational (pre-approved) drug or device within 30 days of surgery

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Vascular Surgery Subjects Treated with EVICELEVICEL ™ Fibrin Sealant (Human)-
Primary Outcome Measures
NameTimeMethod
Specific Safety ParametersUp to 4-weeks post-operatively

* Incidence of graft occlusion

* Incidence of adverse events potentially related to non-graft thrombotic events

* Incidence of bleeding events

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (2)

Memorial Hospital

🇺🇸

Jacksonville, Florida, United States

Baptist Health Medical Center

🇺🇸

Jacksonville, Florida, United States

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