A study on effect of oral tolvaptan tablet, which causes free water excretion and increases serum sodium level, to prevent hyponatremia in patients undergoing TURP surgeries.
Not Applicable
Completed
- Conditions
- Health Condition 1: N998- Other intraoperative and postprocedural complications and disorders of genitourinary system
- Registration Number
- CTRI/2019/04/018808
- Lead Sponsor
- Dr Badri Prasad Das
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 84
Inclusion Criteria
1. All adult patients aged 50-75 yrs with good functional status with METS >4,with diagnosis of BPH posted for TURP surgery.
2.Prostate size >60 gms.
3.Surgeries done under monopolar cautery ( M-TURP) and irrigation fluid of 1.5% glycine.
4.Baseline serum sodium level less than or equal to 132meq/lit.
Exclusion Criteria
1.Patients with history of allergy to study drugs.
2.Uncontrolled diabetes mellitus and hypertension
3.H/O Acute MI, any cardiac conditions,EF < 30 %
4.Patients with cerebro vascular diseases, renal diseases and any other endocrine disorders like SIADH causing electrolyte imbalances.
5.C/I for subarachnoid block
7.Prostate surgery lasting less than 30 mins and more than 2 hrs
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method