Open-label, single-center, randomized and parallel-group study to exmamine the effects of tulobuterol and salmeterol on the peripheral airway resistance in asthma.

Phase 4

• Conditions: Bronchial asthma

• Registration Number: JPRN-UMIN000001177
• Lead Sponsor: Kyoto University Graduate School of Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2008-06-06
• Study Completion: 2012-03-01
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Not provided

Exclusion Criteria

1. Patients with concomitant respiratory disease that may interfere with evaluation of outcomes 2. Patients with hypersensitivity to salmeterol or tulobuterol 3. Patients with dermal disease potentially intolerant to transdermal medication 4. Patients with hyperthyroidism or cardiovascular disease which preclude a use of beta-agonist 5. Pregnancy or lactation 6. Patients who are considered inappropriate by physicians in charge

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Parameters of impulse oscillometry

Secondary Outcome Measures

Name	Time	Method
1. Indices of pulmonary function 2. Exhaled nitric oxide concentrations 3. degree of dyspnea (using Medical Research Council dyspnea scale) 4. Quality of life (using St. George's Respiratory Questionnaire) 5. ACT(asthma control test) 6. clinical symptoms(such as wheezing)