NCT04258735Unknown不适用
Genetic Characteristics of Metastatic Breast Cancer Patients
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 300
- 试验地点
- 2
- 主要终点
- Genomic profiling of MBC patients
研究概览
简要总结
Genomic analysis for metastatic breast cancer(MBC) patients
- Participant (Inclusion criteria)
- Patients who diagnosed metastatic/stage IV breast cancer
- Patients who were not received treatment for metastatic breast cancer on palliative setting
- Process
(1) Tissue/ Blood sample
- At diagnosis, MBC tissue / blood sample (20cc) will be obtained.
- At disease progression after 1st line treatment for MBC, blood sample (20cc) will be obtained (tissue; optional)
(2) WES, RNASeq, ctDNA, Exosome
- We will analyze genomic characteritics using WES, RNASeq, ctDNA, Exosome.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Sequential
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who diagnosed ad metastatic breast cancer
- •Patients who were not received treatment on palliative setting
排除标准
- •Patients who did not agree this study
- •Patients who did not have any pathologic specimen at MBC diagnosis.
结局指标
主要结局
Genomic profiling of MBC patients
时间窗: 60 months
Gemetic alteration frequency, the association between genetic alteration and survival
次要结局
未报告次要终点
研究者
Young-Hyuck Im
Professor
Samsung Medical Center
研究点 (2)
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