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Clinical Trials/NCT04258735
NCT04258735
Unknown
Not Applicable

Genetic Characteristics of Metastatic Breast Cancer Patients

Samsung Medical Center1 site in 1 country300 target enrollmentJuly 17, 2019
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ConditionsMetastatic Breast Cancer

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Metastatic Breast Cancer
Sponsor
Samsung Medical Center
Enrollment
300
Locations
1
Primary Endpoint
Genomic profiling of MBC patients
Last Updated
6 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

Genomic analysis for metastatic breast cancer(MBC) patients

  • Participant (Inclusion criteria)

    1. Patients who diagnosed metastatic/stage IV breast cancer
    2. Patients who were not received treatment for metastatic breast cancer on palliative setting

  • Process

    (1) Tissue/ Blood sample

  • At diagnosis, MBC tissue / blood sample (20cc) will be obtained.

  • At disease progression after 1st line treatment for MBC, blood sample (20cc) will be obtained (tissue; optional)

    (2) WES, RNASeq, ctDNA, Exosome

  • We will analyze genomic characteritics using WES, RNASeq, ctDNA, Exosome.

Registry
clinicaltrials.gov
Start Date
July 17, 2019
End Date
July 31, 2024
Last Updated
6 years ago
Study Type
Interventional
Study Design
Sequential
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Young-Hyuck Im

Professor

Samsung Medical Center

Eligibility Criteria

Inclusion Criteria

  • •Patients who diagnosed ad metastatic breast cancer
  • •Patients who were not received treatment on palliative setting

Exclusion Criteria

  • •Patients who did not agree this study
  • •Patients who did not have any pathologic specimen at MBC diagnosis.

Outcomes

Primary Outcomes

Genomic profiling of MBC patients

Time Frame: 60 months

Gemetic alteration frequency, the association between genetic alteration and survival

Study Sites (1)

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