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临床试验/NCT03174223
NCT03174223已完成不适用

Influence of Deep Versus Moderate Neuromuscular Blockade During General Anesthesia on 30-day Readmission Rates: A Retrospective Analysis of Patient Chart Data

Leiden University Medical Center1 个研究点 分布在 1 个国家目标入组 460 人开始时间: 2017年6月1日最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
460
试验地点
1
主要终点
Readmission

研究概览

简要总结

Deep neuromuscular block (NMB) has shown to produce superior surgical conditions during various abdominal and non abdominal surgeries. It is however unknown if the application of deep NMB leads to favourable outcome, such as lower rate of postoperative complications in general and surgical infections in specific and ultimately lower readmission rates. In the leiden university medical center, deep NMB is routinely applied for a variety of procedures, most notably laparoscopic abdominal and retroperitoneal surgery, eye surgery and neuro radiologic intervention surgery, since 2014. This retrospective study intends to investigate whether the application of deep NMB for these procedures affects patient outcome and readmission rates.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • deep neuromuscular block
  • moderate neuromuscular block
  • general anesthesia
  • complete anesthesia chart

排除标准

  • incomplete anesthesia chart
  • missing data regarding postoperative complications or readmission

研究组 & 干预措施

Deep neuromuscular block

patients received a continuous rocuronium dose to maintain a depth of neuromuscular block of 1-2 twitches post tetanic count

干预措施: deep neuromuscular block (Drug)

结局指标

主要结局

Readmission

时间窗: 30 days after surgery

readmission to the hospital

次要结局

  • Cost(30 days after surgery)

研究者

发起方
Leiden University Medical Center
申办方类型
Other
责任方
Principal Investigator
主要研究者

Albert Dahan

Clinical Professor

Leiden University Medical Center

研究点 (1)

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