Influence of Deep Versus Moderate Neuromuscular Blockade During General Anesthesia on 30-day Readmission Rates: A Retrospective Analysis of Patient Chart Data
Overview
- Phase
- Not Applicable
- Intervention
- deep neuromuscular block
- Conditions
- Postoperative Complications
- Sponsor
- Leiden University Medical Center
- Enrollment
- 460
- Locations
- 1
- Primary Endpoint
- Readmission
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
Deep neuromuscular block (NMB) has shown to produce superior surgical conditions during various abdominal and non abdominal surgeries. It is however unknown if the application of deep NMB leads to favourable outcome, such as lower rate of postoperative complications in general and surgical infections in specific and ultimately lower readmission rates. In the leiden university medical center, deep NMB is routinely applied for a variety of procedures, most notably laparoscopic abdominal and retroperitoneal surgery, eye surgery and neuro radiologic intervention surgery, since 2014. This retrospective study intends to investigate whether the application of deep NMB for these procedures affects patient outcome and readmission rates.
Investigators
Albert Dahan
Clinical Professor
Leiden University Medical Center
Eligibility Criteria
Inclusion Criteria
- •deep neuromuscular block
- •moderate neuromuscular block
- •general anesthesia
- •complete anesthesia chart
Exclusion Criteria
- •incomplete anesthesia chart
- •missing data regarding postoperative complications or readmission
Arms & Interventions
Deep neuromuscular block
patients received a continuous rocuronium dose to maintain a depth of neuromuscular block of 1-2 twitches post tetanic count
Intervention: deep neuromuscular block
Outcomes
Primary Outcomes
Readmission
Time Frame: 30 days after surgery
readmission to the hospital
Secondary Outcomes
- Cost(30 days after surgery)