Approaching One Health concept through assessing presence of faecal carbapenem-resistant Enterobacterales in humans, farm poultry and water
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- 1. Proportion of faecal carriage of carbapenem-resistant Enterobacterales (CRE) in community, hospitalized patients and poultry, as well as their presence in supply water will be known.
研究概览
简要总结
The aim of this study is to determine the presence of faecal carbapenem-resistant Enterobacterales in humans, farm poultry and water, by collecting the stool samples of humans (from the community and admitted patients), stool samples of poultry, and supply drinking water samples from the community and in and around our hospital. Following that, the antimicrobial resistance patterns of all Enterobacterales strains isolated from the collected samples would be studied. From the patterns thus obtained, a correlation between them would be established to ascertain the fundamental concepts of One Health.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Adults from community who have not received any known antibiotic for at least six months.
- •Adult patients admitted in Medicine wards / ICU who are currently on carbapenem therapy.
- •Fully grown broilers from commercial farms / markets.
排除标准
- •Individuals with any known gastro-intestinal illness.
结局指标
主要结局
1. Proportion of faecal carriage of carbapenem-resistant Enterobacterales (CRE) in community, hospitalized patients and poultry, as well as their presence in supply water will be known.
时间窗: At baseline only
2. The antimicrobial resistance patterns of the isolated CRE will be compared.
时间窗: At baseline only
次要结局
- Type of carbapenemase enzymes & the genes encoding them in the isolated strains will be known(At baseline only)
研究者
Dr Anwesh Pattanaik
Maulana Azad Medical College