Study about the efficacy of medium-chain fatty-acids and a ketone body in humans
Not Applicable
- Conditions
- healthy participants
- Registration Number
- DRKS00030530
- Lead Sponsor
- niversitätsklinikum Münster Klinik für Kinder- und Jugendmedizin, Allgemeine Pädiatrie, Bereich Angeborene Stoffwechselerkrankungen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
age between 18-35 male, female
no known metabolic disease
no intake of medication
no chronic illness
normal weight
no mental/verbal limitations
no ketogenic diet
no intake of coconut oil
signature of information sheet
Exclusion Criteria
pregnancy/lactation
paticipation on other studies
intake of medication
heavy underlying diseases
mental diseases
metabolic diseases, chronic diseases
adipositas
blood donation in the last 3 months
gastrointestinal diseases
intolerance of lactose-free milk
allergies agains Gummi Arabicum
veganism
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in ketone body (BHB) concentrations over time; measured as difference between baseline (t0) and maximum.<br>
- Secondary Outcome Measures
Name Time Method test of cognitive performance,<br>weight, hight, BMI<br>Vital parameter (blood pressure, pulse)<br>Blood parameter<br>Ketonebodies: Acetoacetat, ß-Hydroxybutyrat (ßHB)<br>Free fatty acids: C8- und C10-levels<br>lipidmetabolism:<br>Cholesterin, HDL, LDL, Triglyceride<br>carbohydrate metabolism: Insulin, Glucose<br>acids-base-analysis:<br>Osmolality, Magnesium, Calcium