Assessing the Efficacy of Injectable Platelet Rich Fibrin Delivered Chlorhexidine in Treating Periodontal Pockets

Phase 3

Not yet recruiting

Conditions: Chronic periodontitis,

Registration Number: CTRI/2025/06/088587

Lead Sponsor: Government Dental College Raipur

Brief Summary: The study is designed to measure the efficacy of Injectable platelet rich fibrin as a local delrug delivery of drug chlorhexidine in the periodontal pocket the different groups have been allocated to determine the comparison and effectiveness of injectable platelet rich fibrin as a local drug delivery system as it is autologous in nature . Four Different groups include use of scaling and root planing and Injectable platelet rich fibrin and chlorhexidine.other group includes the use of scaling and root planing and xanthan based chlorhexidine. other group includes the use of scaling and root planing and injectable platelet rich fibrin and the last group includes patirnts with scaling and root planing only.The study will evaluate the effectiveness of injectable platelet rich fibrin as a vehicle for delivery of chlorhexidine will cause effective release of drug in periodontal pocket with improvement in clinical and microbial parameters at follow up.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 88

Inclusion Criteria

participants will be chosen on the basis of systemically healthy individual diagnosed with periodontitis stage II grade B with probing depth of more than 5 mm in at least two sites.

Exclusion Criteria

Patients with hemogolobin level less than 11 mg/dL and having habit of smoking and pregnant women or patients under any antibiotic or anti inflammatory therapy.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
of chlorhexidine will cause effective release of drug in periodontal pocket with	15 months
improvement in clinical and microbial parameters at follow up.	15 months
: Injectable platelet rich fibrin (iPRF) as a vehicle for delivery	15 months

Secondary Outcome Measures

Name	Time	Method
Injectable platelet rich fibrin (iPRF) based local	chlorhexidine delivery will have better or comparable effectiveness when

Trial Locations

Locations (1): Government Dental College Raipur
🇮🇳
Raipur, CHHATTISGARH, India
Government Dental College Raipur
🇮🇳Raipur, CHHATTISGARH, India
Dr Alka Snehil
Principal investigator
06268458262
alkasnehil10@gmail.com