跳至主要内容
临床试验/CTRI/2025/06/088587
CTRI/2025/06/088587尚未招募Phase 3 4

Evaluation Of Injectable Platelet Rich Fibrin As a Novel Vehicle For Local Delivery Of Chlorhexidine In Periodontal Pocket: A Randomized Controlled Clinical Trial

Government Dental College Raipur1 个研究点 分布在 1 个国家目标入组 88 人开始时间: 2025年6月18日最近更新:
适应症

试验速览

阶段
Phase 3 4
状态
尚未招募
发起方
入组人数
88
试验地点
1
主要终点
: Injectable platelet rich fibrin (iPRF) as a vehicle for delivery

研究概览

简要总结

The study is designed to measure the efficacy of Injectable platelet rich fibrin as a local delrug delivery of drug chlorhexidine in the periodontal pocket the different groups have been allocated to determine the comparison and effectiveness of injectable platelet rich fibrin as a local drug delivery system as it is autologous in nature . Four Different groups include use of scaling and root planing and Injectable platelet rich fibrin and chlorhexidine.other group includes the use of scaling and root planing and xanthan based chlorhexidine. other group includes the use of scaling and root planing and injectable platelet rich fibrin and the last group includes patirnts with scaling and root planing only.The study will evaluate the effectiveness of injectable platelet rich fibrin as a vehicle for delivery of chlorhexidine will cause effective release of drug in periodontal pocket with improvement in clinical and microbial parameters at follow up.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Participant Blinded

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • •participants will be chosen on the basis of systemically healthy individual diagnosed with periodontitis stage II grade B with probing depth of more than 5 mm in at least two sites.

排除标准

  • •Patients with hemogolobin level less than 11 mg/dL and having habit of smoking and pregnant women or patients under any antibiotic or anti inflammatory therapy.

结局指标

主要结局

: Injectable platelet rich fibrin (iPRF) as a vehicle for delivery

时间窗: 15 months

of chlorhexidine will cause effective release of drug in periodontal pocket with

时间窗: 15 months

improvement in clinical and microbial parameters at follow up.

时间窗: 15 months

次要结局

  • Injectable platelet rich fibrin (iPRF) based local(chlorhexidine delivery will have better or comparable effectiveness when)

研究者

发起方
Government Dental College Raipur
申办方类型
Research institution and hospital

研究点 (1)

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