Study of Genetic Polymorphisms in Thai HIV-1 Infected Patients on SQV/r
Completed
- Conditions
- HIV Infections
- Interventions
- Genetic: identify genetic polymorphism in Thai HIV infected
- Registration Number
- NCT00476502
- Brief Summary
Study of genetic polymorphisms of CYP #A and MDR-1 genes in Thai HIV-1 infected patients on saquinavir/ritonavir.
- Detailed Description
Genetic polymorphisms will be investigated by polymerase-chain reaction (PCR) and drug levels of saquinavir will be determined by high phase liquid chromatography with UV-detected (HPLC).
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 250
Inclusion Criteria
- HIV-infected persons who have been enrolled in the Staccato study
- On low-dose ritonavir boosted saquinavir at the time blood samples are collected
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Exclusion Criteria
- Inability to understand the nature and extent of the study and the procedures required
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description 1 identify genetic polymorphism in Thai HIV infected patients involved in structured interruption therapy
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
The HIV Netherlands Australia Thailand Research Collaboration (HIV-NAT)
🇹ðŸ‡Bangkok, Thailand