NCT00476502已完成不适用
Study of Genetic Polymorphisms of CYP 3A and MDR-1 Genes in Thai HIV-1 Infected Patients on Saquinavir/Ritonavir
The HIV Netherlands Australia Thailand Research Collaboration1 个研究点 分布在 1 个国家目标入组 250 人开始时间: 2006年2月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 250
- 试验地点
- 1
研究概览
简要总结
Study of genetic polymorphisms of CYP #A and MDR-1 genes in Thai HIV-1 infected patients on saquinavir/ritonavir.
详细描述
Genetic polymorphisms will be investigated by polymerase-chain reaction (PCR) and drug levels of saquinavir will be determined by high phase liquid chromatography with UV-detected (HPLC).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •HIV-infected persons who have been enrolled in the Staccato study
- •On low-dose ritonavir boosted saquinavir at the time blood samples are collected
排除标准
- •Inability to understand the nature and extent of the study and the procedures required
研究者
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Impact of Raltegravir on HIV-1 cDNA Slope Following Antiretroviral Therapy (ART) InitiationHIV-1NCT01168167Christoph Stephan20
撤回
不适用
HLA-B35 Alleles and AIDSHIV-1AIDSNCT00340223National Cancer Institute (NCI)
已完成
4 期
Influence of the MDR1 Genotype on Blood Levels of Indinavir and Saquinavir in Healthy VolunteersHealthyHIV InfectionsNCT00050180National Institutes of Health Clinical Center (CC)81
已完成
不适用
Analysis of HCV DAA resistance mutations in HIV and HTLV-1 superinfection casesPatients HCV RNA is positive, and the HIV antibody or HTLV-1 antibody-positive,JPRN-UMIN000017059agasaki University Hospital28
已完成
不适用
Influence of Genes on Sirolimus Metabolism in Patients With Kidney TransplantationRenal TransplantNCT00352547National Institutes of Health Clinical Center (CC)93
